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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

IRSJ Research fellow embarks on historic ‘voyage’

2017-12-11

Prof John T Grider, making the maritime past alive again in the minds
of a new generation.
Photo: Eugene Seegers

Prof John Grider, Associate Professor of History at the University of Wisconsin-La Crosse in the USA and a Research Fellow in the Institute for Reconciliation and Social Justice (IRSJ) at the University of the Free State (UFS), has launched a book based on more than a decade of research into the Pacific maritime labour identity. His monograph, entitled A Foreign Voyage—Pacific Labour Identity, 1840-1890, delves into the history of the maritime industry, not only as a vehicle for expanding the processes of capitalism, colonialism, industrialisation, and globalisation, but is also exploring the impact of this industry on the shifts in gender, race, class, and technology.

As a student in Colorado, a homesick Grider tried to connect with his coastal roots via research. “Before I started to explore the maritime history, I thought of the ocean as a type of boundary that you sometimes need to cross. The truth is that globalisation happens on ships.” Prof Grider’s passion for Pacific maritime labour identity generates colourful discussions on the topic. Masculine sailors confronted by technological de-skilling that corroded away their identity, come to life as he talks and writes. “I try to show students that history is more than a story about the powerful few, and that everyday people, who may seem powerless, play a major role in shaping the past and the future.”

This monograph is based on first-hand, previously unpublished accounts of daily life at sea, often from ships’ logs and the diaries kept by the men who sailed them. The culmination of much painstaking research and supporting evidence, this book investigates the complex interplay between gender, class, and race sourced from the narratives of men who found themselves working in the transforming Pacific maritime industry during the mid-nineteenth century. A powerful lesson to be learnt from this fascinating segment of maritime labour history, is adaptability, “especially in today’s rapidly changing labour world”, Prof Grider says.

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