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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Project aims to boost science pass rate

2009-01-19

Attending the launch of the HP grant of about R1 million to the UFS are, from the left: Mr Leon Erasmus, Country Manager for HP Technology Services in South Africa, Prof. Teuns Verschoor, Acting Rector of the UFS, and Mr Cobus van Breda, researcher at the UFS's Centre for Education Development and manager of the project.
Photo: Lacea Loader

The University of the Free State (UFS), in partnership with computer giant Hewlett Packard (HP), wants to boost the pass rate of its science students by using mobile technology.

The UFS is one of only 15 universities across Europe, the Middle East and Africa and the only university in South Africa to receive a grant from HP to promote mobile technology for teaching in higher education valued at USD$ 100,000 (or about R1 million). Altogether 80 universities from 28 countries applied for the grant.

“Last year HP invited a number of selected universities to submit proposals in which they had to explain how they are going to utilise mobile technologies in the redesign of a course that is presented at the university. The proposal of the Centre for Education Development (CED) at the UFS entitled “Understanding Physics through data logging” was accepted,” says Mr Cobus van Breda, researcher at CED and manager of the project.

According to Mr van Breda, students who do not meet the entrance requirements for the three-year B.Sc. programme have to enroll for the four-year curriculum with the first year actually preparing them for the three-year curriculum.

In order to increase the success rate of these students, the project envisages to enhance their understanding of science principles by utilising the advantages of personal computer (PC) tablet technology and other information and communication technologies (ICT) to support effective teaching and learning methodology.

“By using PC tablet technology in collaboration with data-logging software, a personal response system, the internet and other interactive ICT applications, an environment different from a traditional teaching milieu is created. This will consequently result in a different approach to addressing students’ learning issues,” says Mr van Breda.

The pilot project was launched during the fourth term of 2008 when 130 first-year B.Sc. students (of the four-year curriculum) did the practical component of the physics section of the Concepts in General Science (CGS) module by conducting experiments in a computerised laboratory, using data-logging software amongst other technology applications. “The pilot project delivered good results and students found the interactive application very helpful,” says Mr van Breda.

”The unique feature of the latter is the fact that real-life data can be collected with electronic sensors and instantly presented as computer graphs. It can then be analysed and interpreted immediately, thus more time can be devoted to actual Science principles and phenomena and less time on time-consuming data processing,” says Mr van Breda.

The CGS module can be seen as a prerequisite for further studies in physics at university level and in this regard it is of essence to keep looking for new models of learning and teaching which can result in student success. This year the theoretical and practical component of the physics section of the CGS programme will be done in an integrated manner.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
16 January 2009

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