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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Politicians must push economic integration within SADC, Mboweni

2009-08-31

The outgoing Governor of the Reserve Bank, Mr Tito Mboweni (pictured), believes that for economic regional integration to be realized among the Southern African Development Community (SADC) countries, the political leadership of the region should play a pivotal role.

Mr Mboweni delivered the CR Swart Memorial Lecture, the oldest lecture at the University of the Free State, on the topic: “Seeking greater political and economic integration in Southern Africa in challenging and turbulent financial times”.

He said the necessary macro-economic convergence accords must be put in place for regional integration to take place.

These accords, he said, should be supported by prudent fiscal policies, financial balances among SADC countries, and the implementation of policies which will minimize market distortions.

“In the crafting of the macro-economic policies of the region we have to ensure that market certainty is maintained,” he said.

He said as governors of central banks in the region they have agreed that to achieve these objectives they first have to attain a free trade area.

“When the proposals were drafted the idea was that in 2008 we should have achieved a free trade area,” he explained. “Now we are behind in that regard, meaning that a free trade area has been formally and officially declared but the implementation thereof is behind schedule.”

Mr Mboweni said they were supposed to have a SADC-wide customs union in 2010, a SADC common market in 2015 and a monetary union in 2016.

“In order for us to move towards the regional integration agenda it is clear that there has to be a far greater intra-African trade than is the case now,” he said.

“In Southern Africa most of the trade is with South Africa and the other countries do not trade much with or amongst each other.”

He also said because the South African currency is legal tender in countries like Lesotho, Namibia and Swaziland, they have developed a comprehensive set of proposals with these countries to deal with this matter.

“Our proposals basically center on the creation of a common central bank for South Africa, Lesotho, Namibia and Swaziland which, if created, would form a good basis for the establishment of a SADC-wide central bank.”

He said the macro-economic convergence criteria will not help achieve regional integration without the region’s political will.

“There has to be a commitment by the political leadership in Southern Africa to do the basic things that need to be done for the development of the region,” he said.

“That is where the notion of a developmental state must come in in support of these regional integration initiatives. There is no gain in just shouting developmental state if the basic issues supportive of development are not done.”

Mr Mboweni will leave the Reserve Bank in November this year.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za
31 August 2009

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