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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

Summer programme a first outside Austria
2012-12-06

 

Mr Derek Hanekom, Minister of Science and Technology
Foto: Johan Roux

05 Desember 2012

People often fight about their differences, like skin colour, religion and more. “These differences are minute. We must celebrate our common ancestry and commit ourselves to a common destiny. Your work can make a difference.” This is according to Mr Derek Hanekom, Minister of Science and Technology.

He opened the Southern African Young Scientists Summer Programme (SA-YSSP) at the Bloemfontein Campus on Sunday 2 December 2012. The UFS is the first institution outside Austria to host the Summer Programme. A total of 19 young researchers from 17 countries will be hosted by the UFS until 28 February 2013. Researchers in the programme are, among others, from South Africa, Egypt, China, Italy, Sweden, Iran, Hungary, India, the USA and Indonesia.

The programme will form part of an annual three-month education, academic training and research capacity-building programme jointly organised by the International Institute for Applied Systems Analysis (IIASA), based in Austria, the National Research Foundation (NRF) and the Department of Science and Technology (DST). IIASA is an international research organisation that conducts policy-oriented scientific research in the three global problem areas of energy and climate change, food and water and poverty and equity. South Africa’s engagements with IIASA, specifically with regard to the SA-YSSP, relate primarily to the DST’s Ten-Year Innovation Plan.

Mr Hanekom spoke about the impact the growing global population, which is expected to grow from 7 billion in 2012 to 9 billion in 2050, has on natural resources. “We use purified water to flush our toilets while other people do not have clean drinking water. We cannot carry on like this. Somewhere it must stop, if we do not want to be responsible for the 6th great extinction. We must know how our systems impact on each other.

“We can do things differently and better and should endeavour that other people enjoy luxuries we take for granted,” he said.

He urged the researchers to believe that they can make a difference, share knowledge and translate the knowledge into plans.

Prof. Dr Pavel Kabat, Director/CEO of IIASA, said the summer programme was presented outside Austria for the first time, with plans to expand to Brazil and China in future. Twenty countries are represented on the IIASA board, with more than 3 000 researchers associated with the organisation.

IIASA was launched in 1972 in the days of the Cold War as a “science bridge” between the West and the Soviet Union. It served as a “think tank” for various issues that needed to be resolved. Its mission was reconfirmed after the fall of the Berlin Wall in 1989.

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