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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Applications for the Vice-Chancellor's Prestige Programme for 2013/2014 now open

2012-12-06

This highly prestigious programme, led by the Vice-Chancellor of the University of the Free State, seeks to identify, develop and promote the next cohort of the most promising and talented UFS academic members of staff who obtained a doctoral degree within the last five years. These are young scholars who have chosen academic careers and who are focused and determined to become senior academics in their respective disciplines.

Once identified, these scholars will be put through an intensive programme of academic and scholarship support that includes an advanced residential programme, exposure to leading scholars, intensive reading and writing programmes, high-level seminar participation and presentation, nuanced publication schedules and personal mentoring and advice.

The selection process is highly competitive, and aimed at those young scholars with the potential to obtain upper-level ratings (Y1 and P). The selection criteria include the following:(1)

1. Recently obtained a PhD degree.

2. Evidence of an active publication record.
3. Early recognition of scholarly work, e.g. successful funding/grant applications and academic awards.
4. The early development of a post-doctoral intellectual project that shows evidence of scholarly “potential” (defined by the NRF Y-category).
5. Indication of the young scholar’s understanding of what their envisaged postdoctoral endeavours will contribute to the body of knowledge.

This period of support will run over a cycle of two years after which a new intake of next generation professors will be selected.

While this cohort will be selected for an intensive programme, ongoing development and support of all young scholars will continue. The selected scholars will reflect a balance of young academics from the humanities (broadly defined, including education, law, theology and the social sciences) and the natural sciences (broadly defined, including the agricultural and health sciences).

Call for Applications

This is a call for applications for the Vice-Chancellor’s Prestige Programme for 2013/2014. Candidates are invited to submit applications. No nomination is required, but deans and heads of department will also be asked to invite young scholars to apply. Complete applications are due by Monday 21 January 2013. A full application will include the following documentation:

1. A complete curriculum vitae of the candidate.
2. A complete exercise of intent comprising the following:
2.1   Select two journal articles (copies of which to accompany the application) in the area you have identified for your intellectual focus post PhD. These articles have to be selected from journals of international standing in your field.
2.2   The articles need to be summarised (250 words each), and
2.3   Two questions have to be identified that you would want to pursue in relation to your intended project.
2.4   This is followed by a brief, critical summary of a hundred lines maximum to indicate how these articles inform, integrate or provoke your planned future research.

Submission and contact address

A paper copy of the application must be submitted to the Vice-Chancellor’s secretary, Ms Melissa Coetzee, in the Main Building by 16:00 on Monday 21 January 2013 and an electronic copy of your entire application to the administrative assistant, Mr Albert Nell:nella@ufs.ac.za. You will be contacted to acknowledge receipt. Candidates will be informed of the outcome in February. Further information on the Vice-Chancellor’s Prestige Scholar Programme can be directed at any of the following co-directors (in alphabetical order):

Prof Jackie du Toit, Prof Neil Roos, Prof Aldo Stroebel or Prof Corli Witthuhn.

[1] The VC reserves the right to nominate young scholars to the programme and also to invite scholars to a panel interview to evaluate personal qualities, professional commitment and academic ambition.

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