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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

Official opening: UFS earmarks R10-million to support national priorities
2006-02-06

 

The University of the Free State (UFS) is to align key areas of its academic and research efforts with national priorities through the introduction of five strategic clusters which would be funded by seedmoney of R10-million in 2006.

Speaking at the Official Opening of the UFS on Friday (3 February 2006), the Rector and Vice-Chancellor, Prof Frederick Fourie, said the academic and research work that will be done in the five strategic clusters would contribute to the development of Mangaung, the Free State, South Africa and Africa.

 “It makes sense to concentrate the university’s human resources, our infrastructure, financial resources and intellectual expertise to ensure that the UFS makes a contribution to the country and the African continent,” Prof Fourie said.

“Strategic clusters will be organised on the basis that these areas of knowledge could become in the short term the flagships of the UFS, meaning those areas where the university currently has or in the very near future is likely to have some competitive advantage,” Prof Fourie said.

According to Prof Fourie, this strategic-cluster approach will be in line with the approach being designed by the National Research Foundation (NRF) to take national priorities into account and would enhance the quality of scholarship at the UFS.

The five strategic areas in which research and academic investment at the UFS will be clustered are the following:

Enabling technologies / Technology for the future;
Food production, quality and food security for Africa;
Development;
Social transformation;
Water resource and ecosystem management;

“Such strategic clusters are understood not only as research areas but as areas that also encompass strong undergraduate and particularly postgraduate teaching and a potentially solid scientific basis for service learning and community service research,” Prof Fourie said.

Within each of these clusters specific niche areas will be identified. Clusters could focus on one or more aspects of a particular discipline or could involve more than one discipline in researching a particular issue.

He said not all academic work and research being done at the UFS would be clustered in this way. Sufficient resources and support have been put in place for general research excellence in the past five years.

“Some of the spin-offs can have an important impact on industrial development, for example in the chemicals industry and may also create a basis for cooperation with provincial, national and international partners,” he said. 

Media release
Issued by: Lacea Loader
Media Representative
Tel:   (051) 401-2584
Cell:  083 645 2454
E-mail:  loaderl.stg@mail.uovs.ac.za
5 February 2006

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