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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

UFS launches a Small and Medium Enterprise (SME) Observatory, first of its kind in South Africa

2013-12-04

In cooperation with its partners, the Centre for Development Support at the University of the Free State (UFS), launched the SME Observatory at a function on the Bloemfontein Campus. This initiative is the first of its kind in South Africa.

According to Willem Ellis, Director of the Centre for Development Support, this is a public-private partnership between the UFS, the International Labour Organisation (ILO) and the Department of Economic Development, Tourism and Environmental Affairs (detea), which aims to gather information for research on small and medium enterprises. “With this research we will endeavour to empower policy formulators to make the right decisions in terms of development on a local, provincial and national level,” Ellis said.

Presentations and the panel discussion at the launch covered topics such as:

How many enterprises can survive in a town?
Are entrepreneurs being set up for failure?
Is SMEs the answer to the unemployment question?
The cost of red tape: is SMEs being tied down?

To demonstrate the applicability of the enterprise architect for issues relating to enterprise policy, as well as entrepreneurship strategies, it was decided to focus the pilot phase of the observatory on towns in the Free State. Dr Daan Toerien, research associate at the Centre for Development Support, and Johannes Wessels, Project Manager of the SME Observatory, compiled the report: “50 Towns in the Free State: What the Enterprise Architecture of these towns is telling us about Entrepreneurial Space.”

In his presentation at the launch, Dr Toerien said: “The Enterprise Observatory’s prime goal is to present valuable facts and insights about enterprises in the domains it is observing.” He has developed a database that contains information on a large number of South African towns. He said that studying the enterprise architecture of towns will contribute significantly to inform the policy and strategy debate on LED and enterprise development. “These activities will add valuable data and insights to approach entrepreneurship in the Free State and, after the pilot phase, also in other provinces in South Africa. The Free State government, district and local municipalities, and the consultant fraternity serving them, should find the SME observatory’s activities of value,” he said.

Wessels said that the SME Observatory of South Africa is dedicated to base its arguments on sound theory, science and applied research; to engage policy and decision makers on an evidence-based approach; operate in a politically non-aligned mode in order to mirror truthfully the impact of policies and decisions and to partner with policy makers, entrepreneurs, public administration, think tanks, research institutions, business representatives and NGOs on building networks and alliances to promote an open and competitive enterprise environment.

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