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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

In her inaugural lecture, Prof Helene Strauss explores symbols that reflect our history

2014-02-18

Prof Helene Strauss
The burning tyre – image of promise and disappointment
Photo: Stephen Collett

Prof Helene Strauss did not disappoint in her highly-anticipated inaugural lecture “The Spectacles of Promise and Disappointment: Political Emotion and Quotidian Aesthetics in Post-transitional South Africa”. She posed some very challenging ideas on the promises and disappointments that arouse from apartheid. Prof Strauss pointed to the fact that “… a promise must promise to be kept; that is, not to remain spiritual or abstract, but to produce events, new effective forms of action, practice, organisation, and so forth.”

She underscored the message of her lecture by making use of the image of a burning tyre – a symbol commonly associated with apartheid. This act of ‘necklacing’ is closely connected to the violence and protests of that era. Prof Strauss used this image to represent an array of social concerns: global mass protest, modernity and mobility, waste economies and waste management, environmental destruction, as well as poverty and resistance in varied formats.

Some of South Africa’s greatest artists have used the burning tyre in their work, particularlyBerni Searle and Zanele Muhloi. Not only does it trigger the shadow of the damaging past, but “more recently, it has come to figure also in the spectacles of promise and disappointment that have marked the country’s transitional and post-transitional periods,” Prof Strauss remarked.

Prof Strauss focuses her research on these symbolisms in our history because of “the questions that they raise about the emotional cultures produced in the aftermath of apartheid and for the unique contribution that they make to current debates on political and aesthetic activism.”Her passion for this subject comes from the “affective or emotional legacies of various forms of structural inequality, an interest that owes a sizeable debt to postcolonial, queer and feminist critical theory and creative work of the past hundred or so years.”

Prof Strauss accepted a position at the University of the Free Sate in 2011 and currently works in the Department of English. She is part of the Vice-Chancellor’s Prestige Scholars Programme and holds a PhD from the University of Western Ontario. Previously, she held the position of Assistant Professor in the Department of English and Cultural Studies at McMaster University in Canada, where she resided for 11 years.

Among the guests were Prof Jonathan Jansen, Profs Botes and Witthuhn, lecturers in the Department of English, members of the Faculty of the Humanities, students and some of Prof Strauss’ colleagues from Canada.

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