Latest News Archive

Please select Category, Year, and then Month to display items

The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Renowned forensic scientist speaks at the UFS

2014-04-02

Forensic science is about the truth. At the presentation delivered by Dr David Klatzow, were, from the left: Tinus Viljoen, lecturer in Forensic Genetics, Dr Klatzow and Laura Heathfield, also a lecturer in Forensic Genetics.
Photo: Leonie Bolleurs

It is necessary for more research to be done in the field of forensic science in South Africa. This is according to Dr David Klatzow, well-known forensic scientist, during a lecture delivered at the University of the Free State (UFS) last week.

The university is offering, for the first time this year, a BSc degree in Forensic Science in the Department of Genetics. This three-year degree is, among others, directed at people working for the South African Police Service on crime scenes and on criminal cases in forensic laboratories. Students can also study up to PhD level, specialising in various forensic fields.

There is no accredited forensic laboratory in South Africa. “It is time to look differently at forensic science, and to deliver research papers on the subject. In light of the manner in which science is applied, we have to look differently at everything,” Dr Klatzow said.

Dr Klatzow praised the university for its chemistry-based course. “Chemistry is a strong basis for forensic science,” he said.

A paradigm shift in terms of forensic science is needed. Micro scratches on bullets, fingerprints, DNA, bite marks – all of these are forensic evidence that in the past led to people being wrongfully hanged. This evidence is not necessarily the alpha and omega of forensic science today. DNA, which seems to be the golden rule, can produce problems in itself. Because a person leaves DNA in his fingerprint, it is possible that DNA is transferred from one crime scene to another by forensic experts dusting for fingerprints. According to Dr Klatzow, this is only one of the problems that could be experienced with DNA evidence.

“No single set of forensic evidence is 100% effective or without problems. Rather approach the crime scene through a combination of evidence, by collecting fingerprints, DNA, etc. It is also very important to look at the context in which the events happened.

“A person sees what he expects to see. This causes huge problems in terms of forensic science. For example, if a criminal fits the profile of the perpetrator, it doesn’t follow that this specific criminal is the culprit. It isn’t what we don’t know that gives us trouble, it’s what we know that isn’t so,” Dr Klatzow said.

Back

Economic and Management Sciences

Education

Health Sciences

The Humanities

Law

Natural and Agricultural Sciences

Theology and Religion

Open Distance Learning

Business School

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept