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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

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Prestigious awards, membership and two A-ratings from the NRF indicate a boom in research
2014-12-04

Several UFS researchers were honoured with awards this year. This includes, from the left: Prof Jeanet Conradie from the Department of Chemistry, Dr Aliza le Roux from the Department of Zoology and Entomology on the Qwaqwa Campus of the UFS, Profs Jonathan Jansen, Vice-Chancellor and Rector of the UFS.
Photo: Hannes Pieterse

The University of the Free State (UFS) had several highlights in the field of research this year. This includes two A-ratings, which were awarded by the National Research Foundation (NRF) to Prof Maxim Finkelstein from the Department of Mathematics and Actuarial Science, and Prof Melanie Walker, Senior Research Professor and Director of the Centre for Research on Higher Education and Development (CRHED) and DST/NRF Chair in Higher Education and Human Development.

Prof Finkelstein’s A2-rating makes him the only A-rated researcher in ‘Probability and Statistics’ regarding Mathematical Sciences in the country. Prof Walker was evaluated in the division for Research, Innovation Support and Advancement and received an A1-rating.

Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, considers these ratings as one of the clearest signs that the standard for research across the institution has increased significantly.

Prof Jansen was honoured with the Academy of Science of South Africa’s (ASSAf’s) Science-for-Society Gold Medal for his outstanding achievement in scientific thinking to the benefit of society.

"An award such as this recognises the power of science and scholarship to improve the human condition," Prof Jansen said.

A further highlight at ASSAf’s prestigious annual awards ceremony was the induction of Prof Jeanet Conradie from the Department of Chemistry and Dr Aliza le Roux from the Department of Zoology and Entomology on the UFS’s Qwaqwa Campus as new members of ASSAf.

Prof Conradie was also this year’s first runner-up in the senior category for Distinguished Women Researchers: Physical and Engineering Science in the Department of Science and Technology’s 2014 Women in Science Awards.

Prof Corli Witthuhn: Vice-Rector: Research, describes Prof Conradie as a highly productive researcher who publishes in high-impact journals.

“Not only is she the first female professor in the Department of Chemistry, but she also has extensive international networks and collaboration which elevates the impact of her work even further,” Prof Witthuhn said.

Dr Le Roux is one of ten young researchers inaugurated as members of the South African Young Academy of Science (SAYAS). She was also elected to serve on the executive committee of SAYAS. According to Prof Witthuhn, Dr Le Roux is an outstanding young scientist.

“I am very excited about the young researchers on our Qwaqwa Campus, with Aliza as one of the leaders, and I am looking forward to what they will achieve in the next five years,” she said.

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