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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

School of Medicine expands to provide quality tuition

2015-04-20

The School of Medicine at the University of the Free State (UFS) has recently extended various training platforms to provide continuous quality tuition to students.

Not only does the school boast a world-class dissection hall but now has plans for additional training facilities at two more hospitals.

The new dissection hall was completed in January 2015 with some final finishing touches that will be done shortly. The hall is newly built as the previous dissection hall has been used for undergraduate anatomy training since 1972.

Dr Sanet van Zyl, Senior Lecturer in the Department of Basic Medical Science, says owing to a prospective growth in the number of medical students as well as changing methods in teaching and learning, the need for a new dissection hall became evident to ensure that students get an optimal learning experience during dissection tuition.

“The new spacious dissection hall is equipped with special lighting and modern equipment for the training programme for second-year medical students. The hall is further equipped with modern sound and computer equipment. A unique camera system will allow students to follow dissection demonstrations on ten screens in the hall. Dissection demonstrations can also be recorded, enabling lecturers to put together new materials for teaching and learning.”

In addition to anatomy teaching for under- and postgraduate medical students, the Department of Basic Medical Science also offers anatomy teaching to under-graduate students from the School of Nursing, the School of Allied Health Professions as well as students from the Natural and Agricultural Sciences (such as students studying Forensic Science). The old dissection hall will still be used for the anatomy training of these students.

“The dissection programme for medical students is of critical importance, not only to acquire anatomical knowledge, but also for the development of critical skills and professionalism of our students. As already mentioned, these modern facilities will enable us to be at the forefront of current development in this field. This will benefit both present and future generations of medical students.”

At the same time, Prof Alan St. Clair Gibson, Head of the School of Medicine, announced that lecturing facilities are being developed at the Kimberley Hospital Complex. There are also plans for study facilities at the UFS’s Qwaqwa Campus and Bongani Hospital in Welkom. The UFS’s planning is also well underway for lecturing and residential facilities for students in Trompsburg, where students will receive training at the Trompsburg Hospital.

“We are very privileged to have these facilities and they will help us to provide world class training for students in the School of Medicine,” Prof St. Clair Gibson says.

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