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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Q and A with Prof Hussein Solomon on ‘Terrorism and Counter-Terrorism in Africa’

2015-05-29

Political Science lecturer, Prof Hussein Solomon, has launched his latest book, Terrorism and Counter-Terrorism in Africa: fighting insurgency from Al Shabaab, Ansar Dine and Boko Haram, on Wednesday 26 May 2015 at the UFS.

In his book, Solomon talks about the growing terrorist threat in Africa, with the likes of Al Shabaab, Ansar Dine, and Boko Haram exploiting Africa's vulnerabilities to expand their operations. Explaining both the limitations of current counter-terrorist strategies and possible future improvements, this timely study can be appreciated by scholars and practitioners alike.

Q: If you speak of Al Shabaab, Ansar Dine, and Boko Haram expanding operations, do you see possibilities for their expansion even into South Africa, or is expansion mainly focused on northern African countries?

A: All three movements are operating out of their respective countries. Al Shabaab has attacked Kenya and Uganda and tried to attack the 2010 Soccer World Cup in South Africa. So yes, there is a danger that they are here and, more importantly, newer groups like ISIS are recruiting in SA already.

Q: If the traditional military response is ineffective, what would be a better approach then?

A: What is important is that the force of arms needs to complement the force of ideas. What is being waged is an ideological battle, and, just as the West defeated Communism ideologically in the Cold War, we need to defeat radical Islamism ideologically. In addition, the military response needs to complement the governance and development responses.

Q: External players like the US have insufficient knowledge of the context, what would be the knowledge about context necessary for anyone concerned about the terror problem in Africa?

A: Allow me to give you some examples. The US trains African militaries to fight terrorist groups, but, when they return to their countries, they stage a coup and topple the civilian government. The US does not seem to understand that arming a predatory military and training them makes them more predatory and brutal, which results in civilians being recruited by terrorists, as happened in Mali. Similarly, the US sent arms to the Somali government, and members of that government sold those arms to Al Shabaab terrorists, the very people they were supposed to fight. So the Americans do not understand the criminalisation of the African state, which undermines good governance and promotes terrorism.

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