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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Mandela statues and the issue of public representation

2015-09-04

Prof Grant Parker, Associate Professor of Classics and Co-Director of the Centre for African Studies at Stanford University, USA, presented a public lecture on the Bloemfontein Campus on 27 August 2015, in which he explored the topic of ”Memorialising Mandela after Rhodes Must Fall”. What stories do the multitude of Mandela statues tell us about the man? Our society? Ourselves? These were some of the questions Prof Parker addressed during his lecture.

Paradoxes
Prof Parker discussed some of the paradoxes presented by the Mandela statues. The huge 9m high Mandela statue at the Union Buildings in Pretoria does not necessarily reflect his humility. Iconic statues strewn across the world do not reveal Madiba’s appeal. “Madiba’s charm,” Prof Parker said, “was all about his ability to relate to people of very different backgrounds. People who were his enemies would – to their surprise – find a humanity they were not expecting. It’s very hard to reconcile that with the colossal statues.”

Rhodes Must Fall
On the topic of the Rhodes Must Fall campaign, Prof Parker said that “the debates around it seem to express the frustration of deepening equality in general and lack of demographic change.” He also believes that, although the campaign centres on statues, there are much deeper issues at play that need to be addressed.

Artists should be part of the conversation
Prof Parker also advocated that artists’ voices should be incorporated into the creative processes of public art. “There is a much greater need for creative artists,” he concluded, “to be part of conversations, not only about what we as South Africans want to commemorate, but how we do that. I would very strongly suggest that this be done by non-figural representations.”

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