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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

New Genetics building on Bloemfontein Campus spirals into new frontiers
2015-09-11

On Thursday 3 September 2015, the Department of Genetics hosted the official opening of its new offices on the Bloemfontein Campus of the University of the Free State (UFS).

Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, Prof Neil Heideman, Dean of the Faculty of Natural and Agricultural Sciences, and Prof Paul Grobler, Head of the Department of Genetics cut the ribbon, symbolising the opening of this building with its state-of-the-art facilities.

The new genetics building boasts a new administration block with a reception area, seven offices, a small committee room, and a seminar room for 50 people. Furthermore, the undergraduate laboratory block provides a laboratory for 150 students. The research block has facilities for 30 researchers.

This building also hosts a chemical waste sorting and storage facility. This is a first for the university.

Several sites were investigated for the new building, but due to its size and envisaged second phase, a “green fields” site was found on the western side of the campus. The main entrance caters for visitors from the north, students on foot, and those using the parking area in front of the library. The secondary south entrance is for those who use the dedicated parking area south of the building. The link between these two entrances is the spine of the building, a helix with services/buildings spaced on either side. The helix will be extended in the second phase to keep the circulation and linkage of buildings as simple as possible.

In his opening speech, Prof Grobler gave a breakdown of the history of the Department of Genetics. Today, this department, which opened its doors at the UFS in 1960, is proud of its 131 students and 46 honours students.

According to Major-General Edward Ngokha, Head of the Forensic Science Laboratory, students who graduate from the UFS in the field of genetics make excellent employees. The Forensic Science Laboratory has employed 25 honours students since the BSc Honours degree in Genetics was implemented in 2010.

“The UFS delivers education of high quality and high standards. Thank you for your contribution toward fighting crime by delivering well-prepared, committed employees,” said Major-General Ngokha.

The department presents programmes on population conservation genetics, plant molecular genetics, cytogenetics, forensic genetics, forensic science, human genetics, and behavioural genetics.

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