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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Ivory Coast too dependent on UN to combat violence against women

2015-10-08

During the seminar presented by the Centre for
African Studies (CAS) at the University of the Free State
were, from the left: Thesipo Machabaphala, student in
Gender Studies; Prof Heidi Hudson, Head of CAS;
Dr Peace Medie from the University of Ghana,
guest speaker; and Sesi Mahlobogoane, student in
Gender Studies.

The Ivory Coast is still too dependent on the work of the United Nations (UN) to combat violence against women in the country. There is much talk about ways to address the problem, but the government is still not acting quickly and effectively enough to make a difference in the long term.

These were some of the findings by Dr Peace Medie from the University of Ghana, guest speaker during a seminar series held by the Centre for Africa Studies (CAS) on the Bloemfontein Campus of the University of the Free State on 1 October 2015.

Dr Medie presented a seminar for students in the Gender Studies programme entitled Women, Security, and Justice: a Study of the Ivorian State’s Response to Violence against Women. Prof Heidi Hudson, Head of CAS in the Faculty of the Humanities at the UFS, facilitated the seminar.

For the sake of internationalisation, the CAS often presents guest speakers from outside South Africa to address its students. In addition , Dr Medie is from Africa.

According to Dr Medie, who conducted some 150 interviews during her research over two years, there was a shortage of resources in the Ivory Coast. This is also the case in several other African countries previously involved in war.

She believes the Ivory Coast should do more to combat violence against women successfully.

She said the UN had a great influence on the way people, especially the police, were thinking about the problem - which included sexual violence against women.

“The UN will not be there forever,” Dr Medie said.

“If response depended only on the influence of an international organisation, what would happen when the UN leaves?”

According to Dr Medie, a shortage of active women’s organisations also had a role to play. She was of the opinion that these organisations should put more pressure on the government to ensure better treatment for women.

“Local organisations are needed because it is not sustainable to depend only on the work of the UN.”

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