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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Students have a responsibility in SA, says Ntuli

2016-02-19

Description: 2016 SRC presidents Tags: 2016 SRC presidents

Lindokuhle Ntuli (left), President of the Student Representative Council (SRC) on the Bloemfontein Campus of the University of the Free State (UFS), and Paseka Sikhosana, president of the SRC on the Qwaqwa Campus, are in agreement about their vision for the UFS in 2016.
Photo: Johan Roux

You and I have a role to play in building the new South Africa built upon the Constitution of 1996.

These are the words of Lindokuhle Ntuli, President of the Student Representative Council (SRC) on the Bloemfontein Campus of the University of the Free State (UFS). They echo his and the SRC’s message of a “campus for all students, locally and internationally, irrespective of colour.”

Ntuli and Paseka Sikhosana, president of the SRC on the Qwaqwa Campus, were in agreement about their vision for the UFS in 2016.

According to Sikhosana, a well-known slogan accentuates a feeling of uniqueness at the university. “United in diversity. No wonder we say only a Kovsie knows a feeling,” he says.

“As the SRC, we believe that complete transformation on campus is through promoting a non-sexist, non-racial, but democratic student society that acknowledges diversity and change. That further promotes and embraces one student’s difference in terms of culture, tradition, religion, and sexual orientation.”

A new South Africa

Ntuli means students have a responsibility. He referred to a quotation from Frantz Fanon’s book, The Wretched of the Earth, to illustrate this. Fanon was a revolutionary and writer whose works are influential in post-colonial studies. “Every generation has a mission. It is the responsibility of every generation to discover its mission. Once you have discovered it, you have to fulfil it or betray it into relative obscurity,” Ntuli quoted.

According to him, the South African Constitution holds pious promises of a better life for all, and each citizen needs to help to achieve that.

SRC has open door policy

Ntuli says the UFS remains committed to human embrace, diversity, integration, and human togetherness. He added that the SRC has an open door policy, and will avail itself in helping students.

According to Sikhosana, it is the objective of the SRC to represent the student community in all interactions within the university and externally.

“There is nothing for us, about us, without us students,” he says.

• The above excerpts have been taken from Ntuli and Sikhosana’s respective welcoming speeches to first-year students on the Bloemfontein and Qwaqwa Campuses.

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