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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

University community join hands in the walk for peace and justice

2016-03-02

The Campus Ministries Forum and South African Council of Churches (Free State) have organised a walk for peace and justice from the Main Building to the Callie Human Centre on the Bloemfontein Campus of the University of the Free State (UFS) on Tuesday 1 March 2016. This walk was followed by a prayer meeting at the Callie Human Centre.

Pastors from the Campus Ministries Forum of the South African Council of Churches (Free State) led a group of more than 350 students and staff in praise and worship, followed by prayers in English, Afrikaans, and Sesotho.

A significant gesture at the event was the church leader’s plea for peace and solutions for the conflict at the UFS.

Bishop Monty Mabale, Chairperson of the South African Council of Churches, read an extract from the declaration compiled by the pastors ministering to staff and students at the UFS.

“We are saddened by the violence and vandalism that took place on and off campus. We understand that there are many reasons for frustration and anger, which lead to tensions at the end of last year and again now. We also understand that there are different perspectives on these developments and the complexities underlying to this. However, we cannot agree with the hate speech, the continuous blaming of others, the instigation of violence, and the damage being caused to this precious institution and its commitment to the ideal and practices of reconciliation and a proper education for every student.

“Because we believe in the justice and mercy of God in Christ, let us seek His justice in a compassionate way. Let us resolve to glorify his name in the way we enter into dignified discussions when addressing those matters we perceive to be injustices, and seek for solutions. Let us be critical of our own biased perceptions, opening ourselves to the practice of listening to the viewpoints of others and learning from each other, while discerning the will of God in our society together,” Bishop Mabale said.

The forum and council also wrote a special prayer for UFS students, staff, parents, and management:

Our Father in Heaven
•   You have created us all as unique, special people, each with a great destiny.
•   You have an awesome plan for our University, and value every person working and studying here.
•   We have not respected Your heart and opinion of everyone on campus, and so we have sinned against You.
•   Forgive us where we did not follow Your example of reconciliation, restoration, and forgiveness through the blood of Christ, Your Son, on the cross. We need You to show us what You expect of us: grace, mercy, respect, and tolerance for one another from a place of gratefulness and humility.
•   We are grateful for the opportunity and honour You have given us to be involved in this institution.
•   We repent and accept afresh Your commandment to love You and to love our neighbour as we love ourselves.
•   You are saying to us: “For I know the plans I have for you," declares the LORD, "plans to prosper you and not to harm you, plans to give you hope and a future.” We, as an institution, believe and receive this promise You gave to us.

In Jesus Name we pray,
Amen.

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