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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

UFS Vice-Chancellor’s vision for 2016: R100 million before September

2016-03-03

At the official opening of the University of the Free State (UFS), held on 19 February 2016 on the Bloemfontein Campus, Prof Jonathan Jansen, Vice Chancellor and Rector, announced that his priority for the year is to raise R100 million. Deserving students who cannot afford to study will receive bursaries through the Student Bursary Fund Campaign.

Staff will also have the opportunity to contribute to the fund.

Prof Jansen thanked staff for their hard work in the midst of what he described as “by far the most difficult year for admissions, registration, accommodation, and student finance”. The heightened expectations of students after FeesMustFall and the limited capacity of the university to meet the desires of students took its toll on staff.

Because of the incredible strain taken by staff members, both emotionally and physically, the Vice-Chancellor gave staff the assurance that they will receive spiritual, emotional, and health support.

“Never before have I seen such dedication from all our staff to hold the university together in these trying times,” Prof Jansen said.

“Because of you, we have a record intake of first-year students into the UFS. We have had about 5 000 students on average in the past three years and, as of today, we are nearing 7000 first-years with the strong possibility that we will enroll several thousand more students, once the new South Campus registrations come on line later this year. By mid-2016, we will exceed our own target of 8 000 students,” said Prof Jansen.

He stipulated that it is not only good for the finances of the university but also for the youth of the country who can access a quality university in central South Africa where the safety of its staff and students is a priority.

Another highlight at this event was announcing Dr Christian Williams from the Department of Anthropology as the winner of the 2016 Distinguished Scholar Book Prize for his book, National liberation in postcolonial southern Africa: a historical ethnography of SWAPO’s exile camps.

Amidst the sad episodes of violence and destruction on campuses around South Africa, Prof Jansen highlighted how the UFS will – through a seven-point approach - manage the university during these difficult times:
1.   Doing everything within our capacity to meet the needs of staff and students
2.   Upholding the right to peaceful protest in our democracy
3.   Acting swiftly against any unlawful actions by students or workers
4.   Upholding the authority of the unions (only UVPERSU and NEHAWU)
5.   Finding humane and just solutions to the problem of outsourcing
6.   Not placing the UFS at financial risk by making irresponsible decisions
7.   Maintaining an open door policy.

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