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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

CTL experiments with mobile technology in teaching and learning

2016-05-23

Description: CTL experiments with mobile technology Tags: CTL experiments with mobile technology

On the left is Nokukhanya Nkosi, Researcher and Project manager at the Centre for Teaching and Learning presenting Annah Nggoepe her brand new laptop as part of the project which assesses the impact of personal mobile devices on teaching and learning.
Photo: Supplied

Video clip

Same curriculum. Add technology. Wait and see what happens. This research project which is funded by the Department of Higher Education and Training (DHET) seeks to understand the impact of personal mobile devices (PMD) in teaching and learning.

The University of the Free State (UFS), in conjunction with the University of Cape Town, the University of the Witwatersrand, the University of Johannesburg, and Sol Plaatje University, was approached by the DHET to spearhead this national collaborative project. Investigating whether the financial investment of a PMD on either the part of a university or of students adds value to the teaching and learning experience is the overall objective of the project.

Contemporary education
The Centre for Teaching and Learning (CTL) at the UFS have been taking an active part in the project since 2015, focusing specifically on the use of personal mobile devices in teaching and learning by both staff and students.

At the student level, the study will focus specifically on not just the obstacles that first-generation students face in terms of using technology in teaching and learning, but how institutions can support these students through access to these devices. “In 2015, the CTL conducted the Digital Identity Study of students which highlighted the view that students at the UFS deemed laptops to be the most important PMD in their studies,” said Nokukhanya Nkosi, Researcher and Project manager at the CTL.

In April 2016, thirty students were presented with laptops funded by the project grant. For the next two years, the CTL will assess whether these laptops enable greater flexibility and effectiveness of teaching and learning, both inside and out of the classroom for these students.

Rise of the digital classroom
Annah Ngoepe, a second-year Geography and Environmental Management student taking part in this study, commends the shift from using only textbooks in the past to incorporating technology. “The laptop has the latest applications and programmes, which are convenient for me as a student, because they help in my learning. I can also download textbooks, get summaries of the textbooks, and even other people’s views on a particular subject online.”

Tiana van der Merwe, Deputy Director at the CTL, anticipates that, after two years, the Centre would be able to make not only institutional recommendations, but also recommendations to the National Department of Higher Education.

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