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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

“Every journey begins with the first steps” – Marguerite van der Merwe

2016-07-08

Description: Marguerite van der Merwe Tags: Marguerite van der Merwe

Marguerite van der Merwe, recipient of University of the
Free State Chancellor’s Medal, with Chancellor
Dr Khotso Mokhele, at the Winter Graduation ceremony.
Photo: Johan Roux

Marguerite van der Merwe has dedicated her life to the enrichment and increased quality of life for others. At the University of the Free State’s Winter Graduations on 30 June 2016, Van der Merwe and her brother, Anthony Douglas Osler, were both honoured with Chancellor’s Medals for exceptional service to South Africa and the world beyond our borders. In the early 1980s, she learned about the Alexander Technique and her life since then has been about perfecting the technique and sharing it with others. The Alexander Technique teaches people of any age, gender, occupation or interest, how to be posture-aware and perfect, how to be aware and alert, and how to be calm and discriminating, all of which are part of a practical teaching to integrate these qualities consciously into all our daily human activities.

She walks the walk

She understood the Alexander Technique to be the perfect way to develop the body both physically and mentally, as it develops the higher mental faculties like focus, attention, awareness, consciousness, discrimination, and unfolding of the psyche, thus developing the human potential holistically as a spiritual way of being. She received her training for the technique in Cape Town and London, thereafter she published The Art of Walking, a guide to the Alexander Technique.

Van der Merwe is an internationally-certified teacher of the Alexander Technique, has been offering this work and its application in the spheres of health, education, and performance skills for 30 years, both nationally and internationally.

Van der Merwe says that the South African higher education system should encompass a holistic approach to teaching and educating. Education should envisage a modern vision of education that supports the evolution of the potential of the human being as a holistic system – a competent, skilled, caring, kind individual, developed in physical, mental, emotional and sensorial aspects. She believes that students thus educated will model ‘wholeness’ and ‘humanness’ as they take their place in society, business, education, and entrepreneurship.

Enriching women’s potential

Apart from The Art of Walking, Van der Merwe published EVE-OLUTION, a book to inspire women to listen to their intuition, and empower women to repossess their bodily wisdom, freedom, and authenticity. Van der Merwe proclaims that it is important to liberate women to take charge of their own bodies, minds, and souls. The purpose of the book is to ensure that young women soak up wisdom and encouragement and for older women to express their wisdom, which needs to be respected and listened to.

“Females and feminine roles in society and family are being liberated and acknowledged in the actions of many women as we stand for equal opportunity, equal power, and equality in many fields,” says Van der Merwe.
“Our young women in business and the higher education fraternity, for one, are strong in their views, beautiful in their presence, outspoken in leadership,” Van der Merwe concluded.

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