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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

State of our campuses: UFS closes campuses until Friday 28 October 2016 to readjust academic programme

2016-10-13

The senior leadership of the University of the Free State (UFS) has carefully analysed all the risks facing the university in the current national crisis in higher education, which includes the possibility of losing the academic year. The university management has been engaged in back-to-back meetings with the student leadership, South African Police Service (SAPS), and other stakeholders over the past two days in an attempt to ensure the safety of all parties, and normalise the academic functioning of the UFS. Unfortunately, we have been unable to arrive at an agreement about the resumption of the academic year regardless of the timing of the government response to students’ demands. This is further complicated by the fact that the university has received notice of intention of an interdict to reopen with immediate effect.

Taking all of this into account, the senior leadership of the UFS has decided as follows:

The UFS will not be shutting down for the remainder of 2016. The Bloemfontein and South Campuses will, however, be shutting down from Thursday 13 October 2016 until Friday 28 October 2016. These two weeks will be used for crucial and complex arrangements to be put in place to readjust the academic calendar and ensure that all students can complete their studies.
The academic arrangements are focused on organising alternative modes of delivery of our programmes to support student learning. Academics will be working on readjusting their course materials for this purpose.
The Bloemfontein Campus and the South Campuses will be closed for undergraduate and honours students. Administrative and academic staff will be working, as well as master's and doctoral students.
Students in residence will have to vacate their rooms by 12:00 on Saturday 15 October 2016. Students who need help in this regard must please contact +27 51 401 2001 or send an email to hotline@ufs.ac.za.
Arrangements will be made to accommodate international, master's, and doctoral students.
The specific information about academic programmes will be communicated to students by their respective faculties as it becomes available.

The senior leadership wants to restate its commitment to free education as well as its willingness to stand together with students and other public universities to impress on government the urgency to decide on a time frame for the roll-out of free higher education for the poor and missing middle. During these two weeks the UFS will meet with the leadership of Universities South Africa to coordinate collective action in this regard.

Consistent with this commitment the UFS leadership will roll out a series of activities to inform and educate students and the general public on different models and experiences of providing free higher education.

The UFS is deeply concerned about the possible securitisation of our campus as a way of solving this crisis.

The UFS condemns in the strongest terms violence as a methodology to achieve ends in the context of a democratic state.We are, as always, committed to providing quality education and a conducive environment for learning.

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