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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Translation Day Seminar

2007-10-22

Subverting the West? Engaging language practice as African interpretation.

With the above-mentioned title in mind, about 30 people gathered at the Main Campus of the University of the Free State (FS) in Bloemfontein for a Translation Day Seminar. The day was attended by academics, language practitioners, government departments, students, and other stakeholders in language practice.

Prof. Jackie Naudé, the Programme Director for the Programme in Language Practice at the UFS, gave a short historical overview of developments in research and training in language practice of the past decade. He argued in favour of a socio-constructivist approach to teaching and research in language practice. His point was that students need to be given the opportunity to engage with the complexities of real-life problems, specifically the complexities of the African context.

Dr Kobus Marais, Senior Lecturer in Translation Studies at the UFS, gave an overview of the state of the art of translation research. This meant that language practitioners are agents in communication, not mere conduits of meaning. He argued that translators’ agency implied that they have to make informed choices, the most important of which is whether to indigenise or foreignise when translating. He developed wisdom as a notion in translation, indicating that translators need to be wise to interpret their context and translate in such a way that (Western) ideology does not ride piggy-back on their translations into the African target culture.

Prof. Joan Connoly, Associate Professor in the Centre for Higher Education Development at Durban University of Technology (DUT), took the audience on a breathtaking journey on the topic of oral knowledge. Her presentation showed examples, both European and African oral knowledge and had a clear message for language practitioners: What can Africans learn from the Western mind? Her answer: "Africans can learn how easy it is to loose one’s oral knowledge base. Africans can look at the West and see what the consequences are when a culture loses its oral-based knowledge. Language practitioners have it in their power to consider this possible loss and do something about it."

Lastly, Ms Lolie Makhubu, Head of the Department of Language and Translation at DUT, spoke about enticement in interpreting to use loan words to impress either the audience or peers or clients. Her argument boils down to the interpreter’s attitude towards African culture and language. If Western culture is regarded as higher than African culture, interpreters will be tempted to boast their knowledge of Western culture by means of their choice of words. However, if interpreters are “Proudly South African”, as she put it, they have not need for showing off by using loan words.

Dr Kobus Marais (Senior Lecturer in Translation Studies at the UFS) during the seminar.
Photo (supplied)

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