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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

UFS postdoctoral Fellow expands international opportunities for women in Science Communication

2016-12-13

Mikateko Höppener, postdoctoral Fellow at the
Centre for Research on Higher Education and
Development (CRHED), University of the Free State (UFS),
who was selected as one of five South African women
to participate in the Best Practice in Science
Communication UK study tour.

“Often, the power lies in our own hands as individuals to take the initiative, be curious about opportunities to learn, develop an interest to make a positive contribution in society through our research, and make use of our networks within and outside of academia to effect positive change.”

This is according to Mikateko Höppener, a postdoctoral Fellow at the Centre for Research on Higher Education and Development (CRHED), at the University of the Free State (UFS), who was selected as one of five South African women to participate in the Best Practice in Science Communication UK study tour. This was part of the British Council and Academy of Science South Africa (ASSAf) women in science project.

Höppener said she saw this as an opportunity to expand opportunities for women in Science, Technology, Engineering and Mathematics (STEM). “The whole experience reinforced my conviction that there is a lot of untapped potential for young people to practise and enhance science communication in South Africa for the betterment of our communities,” she said.

During her visit to the UK, Höppener was exposed to an international networking platform of science communication practitioners and stakeholders such as the Director for Development of Vitae, departments at The Royal Society, science journalists at the BBC World Service, policy advisers and public engagement teams at the Welcome Trust, the Director of SciDev.net, and the Science Adviser for STEM Education and Public Engagement at the British Council.

Höppener said each of these meetings had highly interactive presentations and discussions with members of various organisations and the South African delegation.

Being selected for the science communication fellowship and attending the study tour was not only personally and professionally rewarding for Höppener, it also enabled her to pass on what she had learnt to fellow emerging women researchers in South Africa.

Earlier this year, she hosted a WiSTEM (Women in Science, Technology, Engineering and Mathematics) Science Communication and Engagement Workshop at the UFS and through press releases and radio interviews, brought positive attention to the UFS to inspire young women across the country to get involved in science communication training.

“I intend to establish a science communication and engagement centre at the UFS where ongoing training, mentorship and support will be offered to young researchers to learn how to orient their knowledge and research to community development through science communication,” said Höppener.

The Best Practice in Science Communication UK study tour took place from 24 to 28 October 2016 as part of the Newton Fund Professional Development Programme South Africa.

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