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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Centre for Human Rights at UFS geared to make impact in the region

2017-03-02

Description: Centre for Human Rights Tags: Centre for Human Rights

SAHRC situated in the Mabaleng building,
Bloemfontein Campus
Photo: Hannes Pieterse

After approval by the Rectorate, Senate and Council of the University of the Free State (UFS), the Free State Centre for Human Rights (FSCHR) began operations on 1 January 2016 on the Bloemfontein Campus, under the leadership of Prof Leon Wessels, founding member of the South African Human Rights Commission (SAHRC) as the Acting Director of the centre.

Human rights remain, undoubtedly, the dominant moral and political language of our times and thus demands multi-layered scholarly engagement as it influences national and international relations, and sets standards for political and democratic practice.

Establishment of centre fulfilment of court order
Top on the centre’s agenda will be to resolve the debate with the SAHRC relating to the February 2011 post-Reitz agreement of the UFS, which was subsequently made an order of the Equality Court. This order compelled the UFS to establish such a centre. The FSCHR presents new opportunities for cooperation between the FSCHR, the SAHRC and other stakeholders to the benefit of the UFS and the broader community.

Three divisions of the centre to achieve its mandate
The centre consists of three inter-related divisions with the potential to stimulate critical scholarship in the field of human rights through its postgraduate and research division. This is reflected in the centre’s mission to deepen the study of human rights and further its praxes by developing novel methodologies in which traditional human rights issues can be complemented by interdisciplinary and multi-disciplinary approaches.

The Advocacy division of the centre will promote human rights among UFS staff and students, and the surrounding community. The aim is to establish a vibrant human rights culture in and across all campuses in which rights of all are respected and protected.

The Legal Services division will provide trustworthy legal services to individuals and groups whose fundamental rights have been abused, to improve the professional capacity of paralegals, students, counsellors, social workers, candidate attorneys and attorneys, equipping them to deal with cases of infringement of constitutional and human rights and to increase access to justice to rural and indigent communities in the Free State.

Centre key in positioning UFS as a regional leader in human rights issues
The centre, with its inter- and multi-disciplinary approach, has the potential to become one of the flagship projects of the UFS, and will strengthen both the Academic and Human Projects. A UFS human rights centre not only makes sound scholarly and practical sense, it also has limitless symbolic value. The location of one of UFS’s campuses within the city of Bloemfontein (the judicial capital of South Africa) and having partnered with the National University of Lesotho (NUL), is historically and geographically significant. This has a great impact on the UFS, the Free State province as a whole, and the Kingdom of Lesotho.

The FSCHR will be officially launched on 14 March 2017 with Professor Bongani Majola, newly elected chairperson of the SAHRC, as guest speaker.

For further information on the work of the centre, please contact FSCHR@ufs.ac.za / +27 51 401 7216.

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