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UFS students honoured at 2024 Women in Science Awards

23 August 2024 | Story André Damons | Photo Supplied

Thandokuhle Gama, Dr Glen Tylor and Anele Mthembu — Winners: Thandokuhle Gama (left) and Anele Mthembu (right), who were honoured with the DSI-Esther Mahlangu Master's Fellowship at the 2024 SAWiSA, with Dr Glen Taylor, Senior Director: Directorate Research Development (DRD), UFS.

Two postgraduate students from the University of the Free State (UFS) were honoured at this year’s Women in Science Awards (SAWiSA) hosted by the Department of Science and Innovation (DSI).

Thandokuhle Gama, a Master of Medical Science student with specialisation in Pharmacology, and Anele Mthembu, who is working on her master’s degree in Disaster Management in the Disaster Management Training and Education Centre for Africa (DIMTEC), are both recipients of the DSI-Esther Mahlangu Master's Fellowships.

This fellowship is awarded to women scientists and researchers who are pursuing their master’s or doctoral studies and already hold scholarships from the National Research Foundation or other DSI agencies. The fellowships for Gama and Mthembu are worth R75 000 each and can be used towards their tuition fees or to enhance academic programmes by covering the costs of attending conferences or specialised research materials and equipment required to complete their degrees.

Honouring Dr Esther Mahlangu

The prestigious 2024 SAWiSA, which honour the exceptional contributions of women to science, technology, engineering, mathematics and innovation (STEMI) in South Africa, took place on 15 August 2024 in Mbombela. The theme was “Transition towards an Innovation Economy: The Role of Women Leaders in STEM”.

This year, the awards honoured world-renowned artist, Dr Esther Mahlangu, by renaming this year's master's and doctoral fellowships the DSI-Esther Mahlangu Fellowships.

“I feel honoured and grateful for the recognition, although it's been difficult to process what it actually means. It has been an overwhelming experience. It came as a surprise, because when I applied, I was not sure what to expect because these are national awards with many other applicants,” says Gama.

She was nominated by Innocensia Mangoato, lecturer in the UFS Department of Pharmacology and a previous winner at the awards. Gama is doing research on medicinal plants that are used in traditional medicine to treat diabetes.

“Winning this award means that my work thus far is being recognised. It is all through God’s grace. I'm also grateful to everyone who has contributed towards my journey: my family, teachers, mentors and sponsors, and everyone else. It will allow me to continue to advance research in the field of diabetes treatment using traditional medicines or medicinal plants.”

Bettering lives

Mthembu, who was nominated by her mentor, Dr Tlou Daisy Raphela-Masuku, a lecturer at DIMTEC, says it is a fantastic feeling winning this award. “Before the awards, Dr Raphela-Masuku and I dreamt I could win the SAWiSA. But before then, I was surprised and grateful for being acknowledged by DSI as a finalist; I focused on being a DSI finalist, and that winning would be a bonus,” she says.

She continues: “It means a lot to me to win the DSI Master’s Fellowship, as it is a testimony of God’s grace in my life. It is the destiny for helpers God has placed in my life, including my mentor, supervisor, and the DIMTEC postgraduate school. We all won!”

Mthembu is working her master’s thesis on the integration of risk-informed development (RID) and nature-based solutions (NbS) into sustainable human settlements in eThekwini Municipality, KwaZulu-Natal.

“The overarching aim is to evaluate the integration of both these concepts into human settlements’ strategic planning to offer eThekwini Municipality innovative and ecosystem-based approaches to achieving sustainable and resilient human settlements and achieving Sustainable Development Goal (SDG) 11 on building resilient cities.

“I hope to publish my findings and contextualise the enabling environments for RID (EE4RID) Framework in eThekwini Municipality so they can make risk-informed decisions on development and human settlements to achieve SDG 11,” explains Mthembu.

Gama says the aim with her research is to determine if these medicinal plants can treat diabetes by stimulating stem cells to differentiate and become insulin-producing cells. She hopes that through this research diabetes treatment can advance from a level where it is being continuously managed, to a level where we can cure the disease.

News Archive

#Women'sMonth: Save the children

2017-08-10

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach
When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.”

A future without rotavirus vaccination?
Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said.

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