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UFS students honoured at 2024 Women in Science Awards

23 August 2024 | Story André Damons | Photo Supplied

Thandokuhle Gama, Dr Glen Tylor and Anele Mthembu — Winners: Thandokuhle Gama (left) and Anele Mthembu (right), who were honoured with the DSI-Esther Mahlangu Master's Fellowship at the 2024 SAWiSA, with Dr Glen Taylor, Senior Director: Directorate Research Development (DRD), UFS.

Two postgraduate students from the University of the Free State (UFS) were honoured at this year’s Women in Science Awards (SAWiSA) hosted by the Department of Science and Innovation (DSI).

Thandokuhle Gama, a Master of Medical Science student with specialisation in Pharmacology, and Anele Mthembu, who is working on her master’s degree in Disaster Management in the Disaster Management Training and Education Centre for Africa (DIMTEC), are both recipients of the DSI-Esther Mahlangu Master's Fellowships.

This fellowship is awarded to women scientists and researchers who are pursuing their master’s or doctoral studies and already hold scholarships from the National Research Foundation or other DSI agencies. The fellowships for Gama and Mthembu are worth R75 000 each and can be used towards their tuition fees or to enhance academic programmes by covering the costs of attending conferences or specialised research materials and equipment required to complete their degrees.

Honouring Dr Esther Mahlangu

The prestigious 2024 SAWiSA, which honour the exceptional contributions of women to science, technology, engineering, mathematics and innovation (STEMI) in South Africa, took place on 15 August 2024 in Mbombela. The theme was “Transition towards an Innovation Economy: The Role of Women Leaders in STEM”.

This year, the awards honoured world-renowned artist, Dr Esther Mahlangu, by renaming this year's master's and doctoral fellowships the DSI-Esther Mahlangu Fellowships.

“I feel honoured and grateful for the recognition, although it's been difficult to process what it actually means. It has been an overwhelming experience. It came as a surprise, because when I applied, I was not sure what to expect because these are national awards with many other applicants,” says Gama.

She was nominated by Innocensia Mangoato, lecturer in the UFS Department of Pharmacology and a previous winner at the awards. Gama is doing research on medicinal plants that are used in traditional medicine to treat diabetes.

“Winning this award means that my work thus far is being recognised. It is all through God’s grace. I'm also grateful to everyone who has contributed towards my journey: my family, teachers, mentors and sponsors, and everyone else. It will allow me to continue to advance research in the field of diabetes treatment using traditional medicines or medicinal plants.”

Bettering lives

Mthembu, who was nominated by her mentor, Dr Tlou Daisy Raphela-Masuku, a lecturer at DIMTEC, says it is a fantastic feeling winning this award. “Before the awards, Dr Raphela-Masuku and I dreamt I could win the SAWiSA. But before then, I was surprised and grateful for being acknowledged by DSI as a finalist; I focused on being a DSI finalist, and that winning would be a bonus,” she says.

She continues: “It means a lot to me to win the DSI Master’s Fellowship, as it is a testimony of God’s grace in my life. It is the destiny for helpers God has placed in my life, including my mentor, supervisor, and the DIMTEC postgraduate school. We all won!”

Mthembu is working her master’s thesis on the integration of risk-informed development (RID) and nature-based solutions (NbS) into sustainable human settlements in eThekwini Municipality, KwaZulu-Natal.

“The overarching aim is to evaluate the integration of both these concepts into human settlements’ strategic planning to offer eThekwini Municipality innovative and ecosystem-based approaches to achieving sustainable and resilient human settlements and achieving Sustainable Development Goal (SDG) 11 on building resilient cities.

“I hope to publish my findings and contextualise the enabling environments for RID (EE4RID) Framework in eThekwini Municipality so they can make risk-informed decisions on development and human settlements to achieve SDG 11,” explains Mthembu.

Gama says the aim with her research is to determine if these medicinal plants can treat diabetes by stimulating stem cells to differentiate and become insulin-producing cells. She hopes that through this research diabetes treatment can advance from a level where it is being continuously managed, to a level where we can cure the disease.

News Archive

Link between champagne bubbles and the UFS?

2012-11-16

Prof. Lodewyk Kock with an example of a front page of the publication FEMS Yeast Research, as adapted by F. Belliard, FEMS Central Office.
Photo: Leatitia Pienaar
15 November 2012

What is the link between the bubbles in champagne and breakthrough research being done at the Mayo Clinic in America? Nano research being done at our university.

Prof. Lodewyk Kock of Biotechnology says a human being consists of millions of minute cells that are invisible to the eye. The nano technology team at the UFS have developed a technique that allows researchers to look into such a cell, as well as other microorganisms. In this way, they can get an idea of what the cell’s “insides” look like.

The UFS team – consisting of Profs. Kock, Hendrik Swart (Physics), Pieter van Wyk (Centre for Microscopy), as well as Dr Chantel Swart (Biotechnology), Dr Carlien Pohl (Biotechnology) and Liza Coetsee (Physics) – were amazed to see that the inside of cells consist of a maze of small tunnels or blisters. Each tunnel is about 100 and more nanometres in diameter – about one ten thousandth of a millimetre – that weaves through the cells in a maze.

It was also found that these tunnels are the “lungs” of the cells. Academics doing research on yeast have had to sit up and take notice of the research being done at the UFS – to the extent that these “lungs” will appear on the front page of the highly acclaimed FEMS Yeast Research for all of 2013.

The Mayo Clinic, in particular, now wants to work with the UFS to study cancer cells in more detail in order to fight this disease, says Prof. Kock. The National Cancer Institute of America has also shown interest. This new nano technology for biology can assist in the study and development of nano medicine that can be used in the treatment of cancer and other life threatening diseases. Nano medicine uses nano metal participles that are up to one billionth of a metre in size.

Prof. Kock says laboratory tests indicate that nano medicine can improve the efficacy of anti-cancer medicine, which makes the treatment less toxic. “According to the Mayo Clinic team, nano particles are considered as a gold cartridge which is being fired directly at a cancer tumour. This is compared to fine shot that spreads through the body and also attacks healthy cells.”

“This accuracy implies that the chemotherapy dose can be lowered with fewer side effects. The Mayo Clinic found that one-tenth of the normal dosage is more effective against pancreas cancer in this way than the full dosage with a linkage to nano particles. According to the clinic, this nano medicine could also delay the spread of cancer,” says Prof. Kock.

The nano particles are used as messengers that convey anti-cancer treatment to cancer cells, where it then selectively kills the cancer cells. The transport and transfer of these medicines with regard to gold nano particles can be traced with the UFS’s nano technology to collect more information, especially where it works on the cell.

“With the new nano technology of the UFS, it is possible to do nano surgery on the cells by slicing the cells in nanometre thin slices while the working of the nano medicine is studied. In this way, it can be established if the nano medicine penetrates the cells or if it is only associated with the tiny tunnels,” says Prof. Kock.

And in champagne the small “lungs” are responsible for the bubbles. The same applies to beer and with this discovery a whole new reach field opens for scientists.

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