Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
12 December 2024 | Story André Damons | Photo André Damons
Dr Innocensia Mangoato
Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. Here she is with her supervisor and mentor Prof Motlalepula Matsabisa, Director of the University of the Free State (UFS) Department of Pharmacology.

A lecturer and researcher from the University of the Free State (UFS) Department of Pharmacology hopes her research into the use of cannabis in reversing anticancer drug resistance is a step forward into treating various cancers especially in Southern Africa.

Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with the degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. She started her career as a research scientist in the area of African traditional medicines in 2018 and her research received both national and international recognition.

“It’s an amazing (feeling to graduate today). My PhD journey was smooth and beautiful and with mentorship of Prof (Motlalepula) Matsabisa, who groomed me well, I did not shed a tear,” said Dr Mangoato. Dr Gudrun S Ulrich-Merzenich from the University of Bonn in Germany, was her co-supervisor with Prof Matsabisa.

According to the graduation programme, Dr Mangoato, Lecturer and Researcher in the UFS Department of Pharmacology, with her thesis titled Investigating the anticancer and possible resistant reversal effects of cannabis sativa l. extracts in cervical cancer cell lines and modulation of ABC transporters comprehensively explored the therapeutic potential of Cannabis sativa L. in overcoming drug resistance in cervical cancer using in vitro and network pharmacology approaches.

A step forward for treating various cancers

The research looked at the chemical fingerprints and pharmacological targets of C. sativa L. extracts, highlighting its antiproliferative properties against normal non-cancerous cells, cervical cancer cells and the cisplatin-resistant cervical cancer cells. Through PCR analysis, distinct gene expression profiles were identified, revealing the potential effects of combination treatments to counteract cisplatin resistance by downregulating genes associated with drug transporters and crucial signalling pathways. This work provides valuable insights into innovative therapeutic strategies for improving cervical cancer treatment, highlighting new avenues for overcoming resistance and enhancing treatment efficacy though the possible use of plant extracts.

“I hope my research takes a step forward in treating various cancers – especially gynaecology cancers in the Southern Hemisphere in Africa. Hopefully the research can later transcend into clinical trials and hopefully influence more policymakers. We also hope to further develop cannabis to be used as an adjuvant therapy for those drugs that are failing to treat cancer,” says Dr Mangoato, who was the recipient of the Women in Science Master’s Student in 2018.

Her graduation was also a proud moment for Prof Matsabisa, an expert in traditional African medicine, who was like a father to her during her studies. “Prof identified me from my honours degree and walked this journey with me. He has been a great mentor, a father and an amazing supervisor.”

Dr Mangoato says she will for now focus on research only and helping and monitoring upcoming researchers, especially female researchers as there is a scarcity of them her field. 

News Archive

Afrikaans can be learnt online for the first time
2017-11-29

 Description: Afrikaans online Tags: Department of Afrikaans and Dutch, German and French, Prof Angelique van Niekerk, Afrikaans online, Gesellig Afrikaans, VivA 

The launch of the online course in Afrikaans at the University of the Free State
took place in the Centenary Complex at the Bloemfontein Campus on 21 November 2017.
From the left are Profs Francis Petersen, Rector and Vice-Chancellor; Angelique van Niekerk,
Head: Department of Afrikaans and Dutch, German and French; and Gerhard van Huyssteen,
Executive Director: Virtual Institute for Afrikaans.
Photo: Supplied

There is a need among visiting international students and foreign visiting lecturers and researchers to be able to speak Afrikaans. According to Prof Angelique van Niekerk, this is the reason why the Department of Afrikaans and Dutch, German and French at the University of the Free State (UFS) has been offering short courses in Afrikaans on campus for more than 15 years.

As from January 2018, those people wishing to learn Afrikaans outside of the UFS campus will be able to do so fully online. This is the first time that Afrikaans can be learnt fully online. The course is part of a short learning programme, Gesellig Afrikaans 1 and 2, which has been presented at the UFS since 2007. It is presented with the support of the Virtual Institute for Afrikaans (VivA), and Afrikaans can now be learnt as foreign language globally.

Need to speak Afrikaans
 
Prof Van Niekerk, Head of the Department of Afrikaans and Dutch, German and French, believes people who come in contact with the language have a need to learn to speak Afrikaans. “Afrikaans is a vernacular in the workplace, education, and social circles, especially in Bloemfontein, the Free State, and South Africa,” she says.

On average, 15 students per semester are enrolling for the existing contact-based course. Prof Van Niekerk says these students are from countries such as The Netherlands, Belgium, Germany, France, Poland, Lesotho, Zimbabwe, and some are from the East.

English used as teaching medium 
In 2018, the 20-week course will be taught online via the VivA website or on campus through contact sessions (within 13 weeks). “The online course for international students is currently being marketed for the first time, and in 2018 we will officially be enrolling international students for the online course from beyond UFS borders,” says Prof Van Niekerk.

The teaching medium will be English, with all the information and explanations taking place in Afrikaans and English. Supporting material such as Afrikaans films, music, pronunciation guidelines, and continuous self-assessment are part of the online course material.

Click here to see the course structure of the online programme.

Direct enquiries to Prof Van Niekerk at vnieka@ufs.ac.za, or geselligafrikaans@gmail.com or visit www.gesellig-afrikaans.org

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept