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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

Year-long programme to celebrate the story of life and survival
2009-02-13

 
At the launch of the UFS's year-long programme to celebrate the story of life and survival were, from the left: Prof. Schalk Louw, Department of Zoology and Entomology, Prof. Jo van As, Department of Zoology and Entomology, Prof. Maitland Seaman, Centre for Environmental Management, and Prof. Matie Hoffman, Department of Physics. All four are associated with the UFS.
Photo: Hannes Pieterse

A year-long programme to celebrate the 200th anniversary of the birth of Charles Darwin and the 150th anniversary of the publication of his scientifically important book “The Origin of Species” was launched yesterday (the birth date of Darwin) by the University of the Free State (UFS) on its Main Campus in Bloemfontein.

The UFS is the only university in the country that is presenting such an extensive programme on life and survival. Yesterday’s launch programme entailed a portrayal of the life of Darwin and a presentation on what nature tells us about cosmic history. It was the start of a year-long lecture programme in which various departments at the UFS will take part.

“The lecture programme, called “The story of life and survival”, forms a cycle of the progress of man and does not only focus on Darwin. The programme aims to portray the influence of Darwin’s theory of evolution on a wide range of disciplines. We see this as a good opportunity to promote science in its broadest context,” says Prof. Jo Van As, head of the Department of Zoology and Entomology at the UFS.

The lecture programme will include topics such as the geological evolution of our planet, extinction, Darwinian agriculture, the road to civilisation, the proliferation of technology and communication, human demography and the human impact on the environment. It will be concluded in February 2010 with a lecture on the future of evolution.

The programme is spearheaded by the Department of Zoology and Entomology at the UFS, in conjunction with the National Museum and the Central University of Technology.

“Today evolution is no longer considered to be a theory and is widely accepted by most serious scientists as the process responsible for the diversity of life on our planet,” says Prof. Van As.

Complete programme:

26 February 2009: The geological evolution of our planet
13 March 2009: Origin of life, prokaryotes and eukaryotes
24 March 2009: Extinction
16 April 2009: Evolution and biodiversity of plants
30 April 2009: Evolution and biodiversity of animals
14 May 2009: The mechanisms of evolution: Heredity and Natural Selection
28 May 2009: Origin of humankind
4 June 2009: Darwinian agriculture
30 July 2009: Road to civilisation
6 August 2009: Human demography
20 August 2009: Proliferation of technology and communication
10 September 2009: Human impact: On the environment
8 October 2009: Human impact: Resistance, ectoparasites, HIV/Aids, antibiotics
22 October 2009: How to care for the world
12 February 2009: The future of evolution

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
13 February 2009

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