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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

UFS Centenary ends with a weekend of festivities
2005-02-04

The University of the Free State ’s (UFS) Centenary celebrations will come to an end this weekend with a packed programme.

“We celebrated this momentous milestone of the UFS since 28 January 2004 and want to end the year on a high note,” said Mr Jan Ras, Centenary Coordinator.

The weekend will start on Friday 4 February 2005 when Prof Frederick Fourie, Rector and Vice-Chancellor, will open the UFS officially. This will be followed by an historic photo of all staff and students who are on campus that day. All staff will be wearing their academic gowns and the Centenary emblem will be depicted.

The annual Kovsie Engen Rag, with We thank you South Africa as theme, will take place on Saturday 5 February 2005 . The procession will start at 08:00 from the UFS Kovsie church and will move down Nelson Mandela Drive and right into Markgraaff Street exit until it reaches St Andrew’s Street. From here it will turn right into Kings Way where it will stop at the Art Market at 10:00 . Prof Frederick Fourie will then propose a toast on the procession. Afterwards the groups and orchestras will step out and the floats will move through the center of town around Hoffman Square and then back to the UFS campus.

According to Mr Ras a reunion for the Student Representative Council (SRC) will also take place this weekend. About 100 former SRC members are expected to attend the planned activities.

The weekend will be concluded on Sunday 6 February 2005 with a special service of devotion, hosted by all the interdenominational groups on the campus. The service starts at 18:00 for 18:30 in front of the Main Building of the UFS and will be a celebration of praise, thanks and worship, followed by a message from Dr Wollie Grobler. The evening will be concluded with a mass choir and a fireworks display.

“Members of the public are welcome to attend the service of devotion and are requested to bring a candle for the purpose of the mass choir. Although chairs will be arranged in front of the Main Building , people are requested to bring extra pillows and blankets to sit on,” said Mr Ras.

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