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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

Sought-after fellowship for Deaf Kovsie academic
2012-04-25

 

Magteld Smith
Photo: Provided
25 April 2012

For a Deaf person to achieve academic excellence in a sound-dominated world is extremely challenging, but Ms Magteld Smith sees each challenge as another opportunity.

Ms Smith, a Medical Social Researcher at the University of the Free State (UFS), recently received the Herbert H Humphrey fellowship. She is one of only two South Africans to receive this fellowship.
 
The Humphrey Fellowship Program provides mid-career professionals from designated countries around the world with an opportunity to enhance their professional capabilities through participation and is developed specifically for small clusters of Humphrey Fellows at 18 selected US universities.
 
It was initiated in 1978 to honour the memory and accomplishments of the former Senator and Vice-President, Humbert H. Humphrey. Fellows are selected based on their potential for national leadership and commitment to public service, in either the public or private sector. The programme provides a basis for establishing long-lasting productive partnerships and relationships between citizens of the United States and their professional counterparts in other countries, fostering an exchange of knowledge and mutual understanding throughout the world.
 
Ms Smith applied for this fellowship, but was still very surprised when she heard her application was successful.
 
“Upon receiving the news, in my mind I saw an enormous rotating world globe and I asked my Heavenly Father, "What is happening now?" I saw big libraries with books, laboratories, state of the art technology for people with hearing impairments, big cars, big houses, big trucks, big farmers, big women and the White House with big trouble. Furthermore, I saw how the UFS became the world leader of academic excellence and change for people with disabilities with high technology manufacturing and rehabilitation programmes.”
 
Ms Smith says Prof. Jonathan Jansen, UFS Vice-Chancellor and Rector, is a great asset, because for the first time people with disabilities are high on the priority list.

 

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