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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

Another L’Atelier feather in the university’s cap
2013-07-24

 

Pauline Gutter, winner of this year’s Absa L’Atelier competition
Photo: Supplied
23 July 2013

"Dagbreek: Die Dagbreker" - interview with Pauline Gutter (YouTube)

A former Kovsie won the Absa L’Atelier competition – South Africa’s most prestigious art competition – for the second year in a row.

Pauline Gutter, who completed her BA Fine Arts degree at the UFS in 2003, is the second artist from the Free State to win the competition, which is in its 28th year of existence. In 2012, Elrie Joubert, another former Kovsie student from the Department of Fine Arts, won the competition as well.

As overall winner, Gutter receives a cash prize of R125 000 and six months’ residency in the studio apartment Cité Internationale des Arts in Paris, France.

Her winning entry, Die huweliksaansoek, is an interactive work consisting of a 1.8 m high association-rich obelisk, an engraved plaque, a small TV monitor and a farm-line handset. A video of a bull standing in a crush while semen is being drawn from it, is displayed. The viewer is invited to listen in voyeuristically. The soundtrack for the text is composed of statements and comments made by participants in the programme “Boer soek `n Vrou”. The question highlighted by the work, is, “does a farmer choose his future wife in the same way he breeds his stud animals?”

Pauline says her association with the farm, principled parents and strong family ties serve as inspiration for her work. To express her artistic voice in a contemporary environment is to be a close observer of society, she says. “It’s to ask questions which confront the viewer in a provocative way.”

Her advice to new artists is “hard work, sustainability and commitment. Keep looking until you find the place where you fit in.”

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