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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

First-years at South Campus step into a bright future
2015-02-05

Photo: Stefan Lotter

This is the first step to a bright future.

This was the resounding message that welcomed first-year students to the South Campus. “Remember,” Tshegofatso Setilo, Manager of the University Preparation Programme said, “a journey of a thousand miles begins with the first step.” But please do not get discouraged on your way, she urged, because “this is your first step to a bright future.

In his welcoming message, Prof Nicky Morgan, Vice-Rector: Operations at the UFS referred to the South Campus as the giant of the south. “This is one of the trailblazing campuses of the university,” he said. “No doubt what you’ll experience on this campus, you’ll never forget.”

This year, the South Campus boasts with 1 200 first-year students taking part in our University Preparation and Extended Programmes. These programmes allow students – whose matric marks did not reach the required total – the opportunity to study at the University of the Free State (UFS). The result? An astounding rise in pass rates. Some of the students on the South Campus outperform their peers studying at the Bloemfontein Campus, Prof Morgan remarked.

“You’ve got it in yourself. You’ve got the potential to unleash yourself on the world,” Prof Morgan said. You do not always realise the value of something that has come your way, he said. So, every moment you get an opportunity, he advised, use it to shape your future.

Addressing the newcomers’ fears, Prof Morgan urged each student to open themselves to the good and new experiences waiting for them. “When you find yourself in a new space, it always begins with you,” he said. Learn to understand how to live in harmony in different spaces.

Prof Morgan placed great emphasis on his closing remark: “At university, the more questions you seek to have answered – they’re worth more than the answers you have.”

 

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