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13 December 2024 | Story Martinette Brits | Photo Stephen Collett
Dr Francois Jacobs
Dr Francois Jacobs received his Doctor of Philosophy degree in Chemistry on Monday, 9 December.

Dr Francois Jacobs, a 30-year-old PhD graduate, has recently returned from an intensive training workshop in Harwell, Oxford, courtesy of the David Blow Bursary. This prestigious award recognises outstanding African researchers making significant contributions to macromolecular crystallography.

Dr Jacobs earned his Doctor of Philosophy degree in Chemistry on Monday, 9 December. While earning a PhD by the age of 30 was not part of his initial plan, he always aspired to pursue higher education. “From a young age, I had a strong desire to study at university. Once I got there, my ambition shifted towards obtaining a PhD,” he says, reflecting on the journey that led to this remarkable achievement.

Groundbreaking research on cancer and antibiotics

Dr Jacobs’ research addresses some of the most pressing health challenges of our time: cancer and antibiotic resistance. Using crystallography, he investigates the interactions between newly developed anticancer and antibacterial compounds and biological structures such as proteins at the atomic level. This work is vital in combating the growing threat of antibiotic-resistant bacterial infections and advancing cancer treatments.

"For me, it's about seeing humans thrive and reducing the suffering caused by illness," he explains. "I lost my grandmother to cancer, and I hope my work can spare someone else’s loved one from a similar loss."

Prestigious workshop with global experts

The "DLS-CCP4 Data Collection and Structure Solution Workshop," hosted by Diamond Light Source, offered Dr Jacobs an unparalleled opportunity to learn from leading experts in macromolecular crystallography. The workshop covered critical skills such as growing protein and DNA crystals, preventing degradation during data collection, and processing complex data. Participants also gained insights directly from the engineers and scientists behind the facility’s cutting-edge software and synchrotron technology.

“It was an incredible opportunity to learn from some of the brightest minds in the field,” says Dr Jacobs. “Not only did I acquire new skills, but I also forged new collaborations with potential research partners who can help take my work to the next level.”

The David Blow Bursary, which enabled Dr Jacobs to attend this workshop, is awarded to  African researchers conducting impactful macromolecular crystallography studies.

"This training has been transformative," he adds. "It is a fantastic experience for any aspiring researcher, and I’m grateful to have had the chance to learn from these experts. Many researchers who attend workshops like this go on to work at the Diamond Light Source itself. I am eager to see where this training will take me."

A vision for the future

As Dr Jacobs continues his research, he remains driven by the hope that his work will lead to life-saving advancements in healthcare. “I want my research to provide hope and solutions for individuals battling cancer and bacterial infections,” he says.

His achievements exemplify the transformative power of education, research, and collaboration, and his story serves as an inspiration to aspiring researchers across Africa. 

News Archive

School of Medicine expands to provide quality tuition
2015-04-20

 

The School of Medicine at the University of the Free State (UFS) has recently extended various training platforms to provide continuous quality tuition to students.

Not only does the school boast a world-class dissection hall but now has plans for additional training facilities at two more hospitals.

The new dissection hall was completed in January 2015 with some final finishing touches that will be done shortly. The hall is newly built as the previous dissection hall has been used for undergraduate anatomy training since 1972.

Dr Sanet van Zyl, Senior Lecturer in the Department of Basic Medical Science, says owing to a prospective growth in the number of medical students as well as changing methods in teaching and learning, the need for a new dissection hall became evident to ensure that students get an optimal learning experience during dissection tuition.

“The new spacious dissection hall is equipped with special lighting and modern equipment for the training programme for second-year medical students. The hall is further equipped with modern sound and computer equipment. A unique camera system will allow students to follow dissection demonstrations on ten screens in the hall. Dissection demonstrations can also be recorded, enabling lecturers to put together new materials for teaching and learning.”

In addition to anatomy teaching for under- and postgraduate medical students, the Department of Basic Medical Science also offers anatomy teaching to under-graduate students from the School of Nursing, the School of Allied Health Professions as well as students from the Natural and Agricultural Sciences (such as students studying Forensic Science). The old dissection hall will still be used for the anatomy training of these students.

“The dissection programme for medical students is of critical importance, not only to acquire anatomical knowledge, but also for the development of critical skills and professionalism of our students. As already mentioned, these modern facilities will enable us to be at the forefront of current development in this field. This will benefit both present and future generations of medical students.”

At the same time, Prof Alan St. Clair Gibson, Head of the School of Medicine, announced that lecturing facilities are being developed at the Kimberley Hospital Complex. There are also plans for study facilities at the UFS’s Qwaqwa Campus and Bongani Hospital in Welkom. The UFS’s planning is also well underway for lecturing and residential facilities for students in Trompsburg, where students will receive training at the Trompsburg Hospital.

“We are very privileged to have these facilities and they will help us to provide world class training for students in the School of Medicine,” Prof St. Clair Gibson says.

 

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