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12 July 2024 | Story André Damons | Photo André Damons
Research Chairs 2024
Prof Paul Oberholster, Dean: NAS; Dr Glen Taylor, Senior Director for the Directorate Research Development (DRD); Prof Vasu Reddy, Deputy Vice-Chancellor, Research and Internationalisation; and Prof Johan van Niekerk, Vice-Dean for Agriculture in the Faculty of Natural and Agricultural Sciences (NAS); are excited for the new ARC-DALLRD-UFS research chairs.

In a concerted effort to address the challenges and impact of climate change in Southern Africa, the University of the Free State (UFS) together with the Agricultural Research Council (ARC) and the Department of Agriculture, Land Reform and Rural Development (DALRRD) established four new research chairs within the Faculty of Natural and Agricultural Sciences (NAS).

The ARC-DALLRD-UFS research chairs, namely Climate Change and Agriculture, Innovative Agro-processing for Climate-smart Food System, Agriculture Risk Financing and Sustainable Livestock Production, falls under the umbrella of climate change and are part of the established centre of excellence of the ARC and DALRRD on Climate Smart Agriculture.

They will form part of two centres of excellence that the university is also in the process of establishing. The framework for these Agriculture Research Centres of Excellence involves several key components aimed at fostering innovation, collaboration, and impactful research in agriculture. In this case it is Climate Smart Agriculture, enabling them to play a pivotal role in advancing agriculture, enhancing productivity, sustainability, and resilience in the face of global challenges related to climate change.

Prof Johan van Niekerk, Vice-Dean for Agriculture for NAS, and Prof Sonja Venter, from the ARC, are the coordinators for the ARC-UFS-consortium. Joel Mamabolo from the DALRRD is the department’s representative and DALRRD manager in the consortium.

The purpose of the research chairs, he explains, is to conduct high-level research with an aspect of community impact as envisaged in the university’s vision 130. This is the UFS and NAS’s first steps towards creating industry chairs with negotiations between the UFS and the ARC-DALRRD currently taking place for further expansion of the chairs.

Improve research and food security

“The UFS has a long-standing relationship with the ARC and the parties came together to work together to improve research and food security in South Africa and Sub-Saharan Africa. The best way to do this, was by creating research chairs. The ARC saw the university’s expertise in agriculture which also contributed to the ARC establishing the chairs. Our expertise is of such a nature that it does not only influence the sector, but also makes a lasting difference,” says Prof Van Niekerk.

According to him, the ARC and the UFS will collectively manage the research chairs by appointing co-chair principal scientists for each of the chairs in order for the chairs to work together and share resources and expertise. The ARC-DALLRD-UFS research chairs will also work closely together within multidisciplinary research teams and complement each other and in doing so, create a value chain within the agriculture sector.

It will integrate various disciplines including agronomy, genetics, soil science, ecology, pathology economics, socioeconomics horticulture, animal sciences, food sciences and engineering to mention a few. This multidisciplinary approach will foster comprehensive research solutions and innovation at the intersection of different fields and will aim to contribute to sustainable food systems for the future.

The first two chairs; Climate Change and Agriculture, headed by Prof Linus Franke, Head of the UFS Department of Soil, Crop, and Climate Sciences, and the Innovative Agro-processing for Climate-smart Food System, which will be under Dr Alba du Toit, Senior Lecturer in the Department of Sustainable Food Systems and Development, officially started on 1 July 2024, while the remaining two chairs will begin operating in December. The ARC will soon confirm the co-leaders of the various chairs.

The Agriculture Risk Financing research chair will be shared between the Department of Agricultural Economics, within NAS, and the UFS Business School. The Sustainable Livestock Production chair will fall within Prof Frikkie Neser’s Department of Animal Science. To add more credibility, experience and expertise to the ARC-DALLRD-UFS research chairs, Prof Maryke Labuschagne, who is leading the NRF SARChI Chair in Diseases and Quality of Field Crops, has been appointed as mentor.

Prof Vasu Reddy, Deputy Vice-Chancellor, Research and Internationalisation, says: “These chairs mark an exciting opportunity to deepen our understanding of climate change aligned to our expertise in agriculture. The chairs offer us the opportunity to honour and support the leaders who will contribute in powerful ways to the vibrant intellectual life of the faculty, as well as the university, the ARC and DALRRD.

“The chairs also honour the donor whose financial support makes this form of recognition possible. At the UFS we are committed to engaging in global challenges but with a deliberate local focus, energy and drive. I am especially excited that these chairs demonstrate a commitment to the UFS focus on partnerships with industry, communities, the state and other academic and research institutions both nationally and around the world.”

Grateful for the ARC relationship

Through these chairs more collaborators and partners from other universities in the country and globally will be included in the partnership with the aim to bring together internationally renowned scientific experts that will collectively focus to address global challenges and enhance the development of more scientific capacity for the country.

The university, Prof Van Niekerk continues, is grateful for the cooperation and relationship with the ARC and its President and CEO, Dr Litha Magingxa and the executive management team, as well as the DALRRD DG, Mooketsa Ramasodi and the DDG for Agricultural Production, Biosecurity and Natural Resources Management, Dipepeneneng Serage for creating an environment within which the Universities and ARC can collectively contribute towards developing solutions with the DALRRD for key agricultural challenges of the country.

He expressed his gratitude to the Directorate Research Development (DRD) under the leadership of Dr Glen Taylor, for not only their support, but for bringing the parties together and negotiating with the ARC on their behalf. In this regard he wishes to thank Dr Petronella Chaminuka from the ARC as the acting Executive Manager: Research support and coordination for her support, guidance and leadership during the process.

Prof Van Niekerk also thanked Profs Francis Petersen, UFS Vice-Chancellor and Principal, Reddy, and Paul Oberholster, Dean of the Faculty of NAS, for creating the environment and rendering immense support for this programme from the UFS. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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