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17 April 2025 | Story Onthatile Tikoe | Photo Kaleidoscope Studios
Thabiso Khoeli
Dr Thabiso Khoeli, Lecturer in Historical and Constructive Theology at the UFS, celebrates the completion of his PhD.

The University of the Free State (UFS) celebrated one of its own, Dr Thabiso Khoeli, a Historical and Constructive Theology Lecturer in its Faculty of Theology and Religion, when he received his PhD in Theology with specialisation in religion studies during the recently completed April graduation ceremonies. 

Dr Khoeli’s achievement not only marks a personal milestone but also advances the university’s Vision 130, a strategic initiative to position UFS as a research-led institution by its 130th anniversary in 2034. Dr Khoeli’s academic journey is one of resilience, transformation, and a profound commitment to telling African stories from an African perspective. 

 

From uncertainty to purpose

Dr Khoeli’s path into studying Theology was unplanned. As a former KovsieFootball  player, his initial academic interest was in Sports Science. However, after some admission hurdles, he found himself directed towards Theology, a field that soon captured his full attention.

“Honestly, I did not choose Theology, instead it chose me,” he shares. “… Theology whispered to me and said, ‘Do not deviate, Brother. Your calling is here.” Despite initial scepticism, his first semester revealed the intellectual and spiritual depth of the discipline, compelling him to pursue it with passion.

 

A research focus on African voices

His doctoral research, titled ‘Exploring the Zion Christian Church’s Teachings and Qualities in Comparison with Zion Churches’, examines the theological, historical, and cultural distinctiveness of the Zion Christian Church (ZCC), one of the largest and most influential religious movements in Africa. Motivated by a desire to decolonise theology and challenge externally imposed narratives, Dr Khoeli engaged directly with primary sources, including archival materials and interviews with Church elders.

“Africans must now write their own stories and never rely on the findings presented by others,” he says. His work not only fills critical gaps in theological scholarship but also reflects the UFS’s vision of becoming a centre of thought leadership on the African continent.

 

Research shaping teaching

As a Lecturer in Historical and Constructive Theology, Dr Khoeli’s research directly informs his methods of teaching. He approaches the classroom with a decolonised, historically grounded perspective that helps his students engage with both their spiritual heritage and contemporary realities critically.

“My research enabled me to analyse documents and align them to my objective,” he explains. “That is the strategy I use to collect the relevant reading materials to prepare for the students.” His teaching method fosters independent thinking and encourages students to become scholars who are both academically rigorous and socially conscious.

 

Overcoming challenges through community and conviction

Gaining access to the ZCC’s historical documents was a major challenge. The Church’s deep-rooted secrecy required careful relationship-building and persistent effort. But Dr Khoeli remained undeterred. “I intended to leave no stone unturned,” he says. Through perseverance, mentorship, and faith, he accessed essential material for his literature-based study.

He also credits colleagues at the Faculty of Theology and Religion for their belief in his potential at a time when few others would give him a chance. “It feels great,” he reflects. “I don’t have enough words to explain how overwhelming it feels to prove to yourself that you are the greatest.”

 

A vision beyond the doctorate

With his PhD now complete, Dr Khoeli is setting his sights on further research projects that contribute to the reconstruction of African religious history and knowledge systems. He sees his work as part of a larger mission to revive indigenous spirituality and cultural identity in the face of modern erasure.

“Modernity is converting us to be a nation without roots,” he cautions. His aim is to produce scholarship that restores heritage while also responding to the physical and spiritual needs of African communities, one of the fundamental goals of the UFS’s Vision 130.

 

Inspiring the next generation

To current and future UFS students, especially those considering postgraduate study, Dr Khoeli offers this message, with his own story as proof: “Believe in your purpose, even when the path seems uncertain… There is greatness in you.” 

Through his academic excellence, teaching innovation, and dedication to African-centred research, Dr Khoeli exemplifies the values of the UFS’s Vision 130. His journey reflects a university that is not only committed to high-impact research but also to empowering scholars who bring change, both in the academic world and beyond.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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