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29 August 2025 | Story Precious Shamase
One Health research project
Pictured are Prof Steven Belmain, Dr Hayley Thompson, and Prof Lourens Swanepoel during their visit to South Africa to kick off a collaborative One Health research project aimed at addressing rodent-related health risks in townships – an initiative that unites local and international experts in the pursuit of safer, community-driven solutions.

A collaborative research project is underway in South African townships to combat the pervasive rodent problem and its impact on human health. Led by Prof Peter Taylor, Professor-in-Residence in the UFS Afromontane Research Unit and affiliated with the UFS Department of Zoology and Entomology, the initiative brings together experts from the UK's Natural Resources Institute (NRI), including Prof Steven Belmain and Dr Hayley Thompson, and South African institutions such as the UFS and the University of Venda.

This 'One Health' approach acknowledges the interconnectedness of human, animal, and environmental well-being. The team visited laboratory facilities at the UFS campuses in Bloemfontein and Qwaqwa, the latter being near Phuthaditjhaba township – a key research site alongside Lwamando in Limpopo.

The multidisciplinary project involves local farmers and university departments, integrating expertise in advanced techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry, molecular virology and microbiology, genome sequencing, and parasitology. Social scientists, such as Dr Shingirayi Chamisa, a lecturer in the UFS Department of Industrial Psychology, are also involved to understand community perceptions and current rodent control methods, including the impact on mental health.

The research will investigate the health risks associated with rodent infestations, including food contamination with poison residues and fungal toxins, and the transmission of disease to humans and livestock through direct contact or parasites. Practical trials will evaluate methods to reduce food contamination.

Significantly, the project will explore novel and humane rodent control strategies, such as contraceptive baits, offering a safer alternative to rodenticides. Recent concerns about rodenticide-related deaths in townships have increased pressure for safer, ecological solutions.

This research holds significant promise for developing sustainable and effective solutions to mitigate the negative impact of rodent pests on the health and livelihoods of township residents. The international and local collaboration, guided by a holistic 'One Health' perspective, marks a crucial step towards addressing this challenging issue. Prof Taylor expressed his appreciation for the enthusiastic engagement of all collaborators, highlighting the potential for a truly transdisciplinary project to find meaningful and ecologically sound solutions to rodent-borne pathogens and food contamination in South African townships.

News Archive

Darwin lecture focuses on the genetic foundation of evolution
2009-05-22

 
The Department of Genetics at the University of the Free State (UFS) recently made their contribution to the story of life and survival by presenting two lectures on The genetic foundation of evolution. Prof. Johan Spies, Head of the Department of Genetics at the UFS discussed the variation that was created by mutations and how this variation was enhanced by re-combination. He also pointed out that these methods contributed relatively little to the gene pool of a species and that the expansion of the gene pool primarily took place by means of chromosome evolution. The latter also contributed to the creation of isolation mechanisms to prevent hybridism. He further emphasised the multitude of deviations of mendelian heredity, which contributed to more variation within a species.

Prof. Paul Grobler, Associate Professor from this department, next pointed out how natural selection played a role to form new species. He used various examples to indicate how the process took its course, for example, lactose intolerance. He also reported out that the man on the street mostly believed that Darwin with his theory of the survival of the fittest meant that the physically strongest species would survive. It was more a case of the one that could reproduce the fastest and the most, that would survive, he stated.

Present at the occasion were, from left front: Ms Letecia Jonker, student, Prof. Grobler, Ms Paula Spies, lecturer at the Department of Genetics and Ms Zurika Odendaal, junior lecturer at the Department of Genetics; back: Prof. Spies.
Photo: Stephen Collett

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