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29 August 2025 | Story Precious Shamase
One Health research project
Pictured are Prof Steven Belmain, Dr Hayley Thompson, and Prof Lourens Swanepoel during their visit to South Africa to kick off a collaborative One Health research project aimed at addressing rodent-related health risks in townships – an initiative that unites local and international experts in the pursuit of safer, community-driven solutions.

A collaborative research project is underway in South African townships to combat the pervasive rodent problem and its impact on human health. Led by Prof Peter Taylor, Professor-in-Residence in the UFS Afromontane Research Unit and affiliated with the UFS Department of Zoology and Entomology, the initiative brings together experts from the UK's Natural Resources Institute (NRI), including Prof Steven Belmain and Dr Hayley Thompson, and South African institutions such as the UFS and the University of Venda.

This 'One Health' approach acknowledges the interconnectedness of human, animal, and environmental well-being. The team visited laboratory facilities at the UFS campuses in Bloemfontein and Qwaqwa, the latter being near Phuthaditjhaba township – a key research site alongside Lwamando in Limpopo.

The multidisciplinary project involves local farmers and university departments, integrating expertise in advanced techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry, molecular virology and microbiology, genome sequencing, and parasitology. Social scientists, such as Dr Shingirayi Chamisa, a lecturer in the UFS Department of Industrial Psychology, are also involved to understand community perceptions and current rodent control methods, including the impact on mental health.

The research will investigate the health risks associated with rodent infestations, including food contamination with poison residues and fungal toxins, and the transmission of disease to humans and livestock through direct contact or parasites. Practical trials will evaluate methods to reduce food contamination.

Significantly, the project will explore novel and humane rodent control strategies, such as contraceptive baits, offering a safer alternative to rodenticides. Recent concerns about rodenticide-related deaths in townships have increased pressure for safer, ecological solutions.

This research holds significant promise for developing sustainable and effective solutions to mitigate the negative impact of rodent pests on the health and livelihoods of township residents. The international and local collaboration, guided by a holistic 'One Health' perspective, marks a crucial step towards addressing this challenging issue. Prof Taylor expressed his appreciation for the enthusiastic engagement of all collaborators, highlighting the potential for a truly transdisciplinary project to find meaningful and ecologically sound solutions to rodent-borne pathogens and food contamination in South African townships.

News Archive

Doctors make history with unique heart operation
2012-04-04

 

Cardiologists at the university delivered the first Melody pulmonary valve in Africa.
Photo: Evert Kleynhans
30 March 2012

Academics of the Faculty of Health Sciences at the University of the Free State made history in Africa once again this week with the implant of a special pulmonary heart valve.

“Today we are extremely proud Free State citizens,” Prof. Stephen Brown and Dr. Danie Buys from the UFS Department of Paediatrics and Child Health said after they placed the Medtronic Melody pulmonary valve in two young patients at the Universitas hospital in Bloemfontein.

This is the first time in Africa that the Melody valve is placed.

To date there are currently only 3 000 of these valves place in the world.

“It feels incredible to be part of a team of experts from the faculty.”

The Medtronic Melody valve is delivered percutaneously through a catheter from the groin. This operation is for children and young adults who are born with a malformation of their pulmonary valve.

These children often require open-heart surgery at a very young age and later require additional open-heart surgeries to restore blood flow between the heart and the lungs.

Prof. Brown said that of all congenital diseases, heart disease is most common. A lot of children born with heart disease are diagnosed very late and many die without ever receiving specialised care.

In 2011, Prof. Brown and two other cardiologists from the UFS, Prof. Hennie Theron en Dr JP Theron also reached a medical milestone when they were the first cardiologists in South Africa to do a second generation Medtronic CoreValve implant on an elderly patient.
 

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