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29 August 2025 | Story Precious Shamase
One Health research project
Pictured are Prof Steven Belmain, Dr Hayley Thompson, and Prof Lourens Swanepoel during their visit to South Africa to kick off a collaborative One Health research project aimed at addressing rodent-related health risks in townships – an initiative that unites local and international experts in the pursuit of safer, community-driven solutions.

A collaborative research project is underway in South African townships to combat the pervasive rodent problem and its impact on human health. Led by Prof Peter Taylor, Professor-in-Residence in the UFS Afromontane Research Unit and affiliated with the UFS Department of Zoology and Entomology, the initiative brings together experts from the UK's Natural Resources Institute (NRI), including Prof Steven Belmain and Dr Hayley Thompson, and South African institutions such as the UFS and the University of Venda.

This 'One Health' approach acknowledges the interconnectedness of human, animal, and environmental well-being. The team visited laboratory facilities at the UFS campuses in Bloemfontein and Qwaqwa, the latter being near Phuthaditjhaba township – a key research site alongside Lwamando in Limpopo.

The multidisciplinary project involves local farmers and university departments, integrating expertise in advanced techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry, molecular virology and microbiology, genome sequencing, and parasitology. Social scientists, such as Dr Shingirayi Chamisa, a lecturer in the UFS Department of Industrial Psychology, are also involved to understand community perceptions and current rodent control methods, including the impact on mental health.

The research will investigate the health risks associated with rodent infestations, including food contamination with poison residues and fungal toxins, and the transmission of disease to humans and livestock through direct contact or parasites. Practical trials will evaluate methods to reduce food contamination.

Significantly, the project will explore novel and humane rodent control strategies, such as contraceptive baits, offering a safer alternative to rodenticides. Recent concerns about rodenticide-related deaths in townships have increased pressure for safer, ecological solutions.

This research holds significant promise for developing sustainable and effective solutions to mitigate the negative impact of rodent pests on the health and livelihoods of township residents. The international and local collaboration, guided by a holistic 'One Health' perspective, marks a crucial step towards addressing this challenging issue. Prof Taylor expressed his appreciation for the enthusiastic engagement of all collaborators, highlighting the potential for a truly transdisciplinary project to find meaningful and ecologically sound solutions to rodent-borne pathogens and food contamination in South African townships.

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Prestige Scholar hosts Prof John Helliwell of Manchester University
2015-12-08

From left is Prof John R. Helliwell (School of Chemistry, University of Manchester), Dr Madeleine Helliwell (School of Chemistry, University of Manchester), Prof Andre Roodt (Department of Chemistry, University of the Free State) and Dr Alice Brink (Department of Chemistry, University of the Free State).
Photo: Steven Collett

At the invitation of Dr Alice Brink of the Department of Chemistry, Prof John Helliwell, the 2015 Max Perutz Prize winner, and his wife, Dr Madeleine Helliwell, visited the University of the Free State (UFS).
The Helliwells, both chemists of note, took part in a series of lectures and exchanges on the Bloemfontein and Qwaqwa Campuses.
This visit from 9-19 November 2015 was the consequence of Dr Brink’s participation in the Vice-Chancellor’s Prestige Scholars Programme (PSP) initiative to encourage the broadening of the international footprint of the next generation of scholars in the academy.

Two year collaboration

Dr Brink and Prof Helliwell from Manchester University have a standing collaboration going back two years. Dr Brink, an NRF Thuthuka grant holder and a member of the PSP since 2013, has spent almost eight months in Manchester, collaborating with Prof Helliwell on her study of the successful interaction of rhenium tricarbonyl complexes with proteins determined via protein crystallography.
Their collaboration resulted from the close association of Prof Helliwell and Prof Andre Roodt from the UFS Department of Chemistry, both former presidents of the European Crystallographic Association.

Sharing academic expertise

Prof Helliwell, the 2014 American Crystallographic Association Patterson Award winner for his “pioneering contributions to the global development of the instrumentation, methods and applications of synchrotron radiation in macromolecular crystallography”, gave three lectures in the Department of Chemistry, two on the Boemfontein Campus, and the other on the Qwaqwa Campus on 13 November 2015.

Dr Helliwell, former co-editor of the Acta Crystallographica Section C: Crystal Structure Communications journal, consulted with postgraduate students from the Departments of Chemistry and Biochemistry.

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