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25 June 2025 | Story Dr Nitha Ramnath | Photo Lunga Luthuli
Dr Omololu Aluko
Dr Omololu Aluko, Senior Lecturer in the Department of Biostatistics advances health research and collaboration during prestigious fellowship at Ghent University, Belgium.

Dr Omololu Aluko, Senior Lecturer in the Department of Biostatistics in the Faculty of Health Sciences at the University of the Free State (UFS), recently completed a prestigious short research stay at Ghent University in Belgium. The fellowship, hosted in April 2025, was awarded through the highly competitive Africa Platform of Ghent University Association (GAP) funding scheme, with additional support from the UFS International Office. 

A recognised expert in infectious disease modelling, particularly HIV/AIDS research in low-resource settings, Dr Aluko has devoted his academic career to using biostatistics to address pressing health challenges. His selection for this fellowship marks a significant achievement both for his individual research trajectory and for the broader ambitions of the Faculty of Health Sciences and the UFS.

 

Strategic steps towards international collaboration 

The opportunity for the fellowship was first announced in the UFS Digest Newsletter. Motivated by the potential for international collaboration, Dr Aluko began seeking a host at Ghent University whose interests aligned with his own. After several weeks of correspondence with various departments and researchers, a suitable academic collaborator agreed to host him. 

With a host confirmed, Dr Aluko submitted his application, which underwent a rigorous review and selection process. His proposal was shortlisted and ultimately approved. While Ghent University provided partial funding, supplementary financial support was secured through the UFS International Office. Dr Aluko credits the office’s assistance – especially the guidance of Mr Kagiso Ngake, Senior Officer: Partnerships – for helping him successfully secure the necessary resources. 

 

Advancing research in health data science  

During his time at Ghent University, Dr Aluko focused on the application of machine learning algorithms to address public health challenges – an increasingly important field within the Faculty of Health Sciences. His research demonstrated how advanced data analysis techniques can improve health outcomes and optimise treatment strategies, especially in resource-constrained settings. 

Beyond the immediate research achievements, the fellowship laid a foundation for long-term collaboration between the UFS and Ghent University. Key outcomes include: 

  • Opportunities for joint PhD supervision, allowing UFS students to conduct part of their research at Ghent University 
  • Prospects for publishing collaborative research in leading international A1-rated journals 
  • The identification of a promising young research collaborator, paving the way for future academic partnerships 
  • Plans to explore future staff exchange programmes, as new funding calls are announced 

     

A growing partnership in a new academic field 

Dr Annelies Verdoolaege, Coordinator for the Africa Platform at Ghent University, emphasised the broader vision behind the initiative:

“The purpose of these fellowships is to foster structural academic collaboration between Ghent University and partners in Africa. We offer a dedicated amount of seed funding to support short-term mobility, with the aim of building long-term partnerships – through student exchange, joint PhDs, joint funding proposals, and collaborative research publications. 

The UFS is a long-standing partner of Ghent University, especially in Education, Linguistics, and Agriculture. We are delighted that this fellowship has taken place in the field of Data Analysis and Mathematical Modelling - a scientific domain still to be fully developed between our institutions.” 

 

Enhancing UFS’ global research impact 

Dr Aluko’s successful fellowship reflects the high calibre of researchers at the UFS and illustrates the importance of international academic mobility. By securing this competitive opportunity, Dr Aluko not only advanced his own work but also strengthened the UFS’ global research footprint - opening new collaborative avenues and reinforcing the university's growing reputation in health sciences and data-driven research. 

The UFS expresses its sincere gratitude to the Africa Platform of Ghent University and the UFS International Office for their critical support in enabling this milestone. Partnerships such as this are key to fulfilling the UFS’ mission of producing world-class research and fostering meaningful global engagement. 

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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