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19 March 2025 | Story Precious Shamase | Photo Andre Damons
SAMC 2025
Prof Jared McDonald, Associate Professor in the Department of History; Dr Grey Magaiza, Senior Lecturer: Centre for Gender and Africa Studies, and Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the University of the Free State (UFS).

The Second Southern African Mountain Conference (SAMC 2025) commenced on Monday, 17 March amid a tangible sense of anticipation and a collaborative spirit at the Champagne Sports Resort, nestled in the heart of the Maloti-Drakensberg. Delegates from across the region and beyond gathered, setting the stage for a week of insightful discussions and collaborative exploration under the theme, ‘Southern African Mountains – Overcoming Boundaries and Barriers.’

Hosted by the University of the Free State (UFS) and its Afromontane Research Unit (ARU), the conference opened with a series of welcome statements that emphasised the global significance of mountain ecosystems. Prof Ralph Clark, SAMC 2025 Conference Chair and Session Chair, initiated the proceedings, setting the tone for a conference focused on actionable solutions.

Collaboration transcends mountain borders

The global reach of the conference was immediately evident, with welcome addresses from key partners. Prof Roland Psenner, President of Eurac Research – speaking on behalf of the Global Mountain Safeguard Programme (GLOMOS) – highlighted the importance of international collaboration. Alex Hickman, Chairman of the African Mountain Research Foundation (AMRF), highlighted the critical work being done on the ground. Notably, a recorded message from Prince Harry, Duke of Sussex, in support of the AMRF resonated with attendees, further amplifying the message of the conference.

Prof Hester C. Klopper, Vice-Chancellor and Principal of the UFS – speaking on behalf of the ARU – stressed the significance of the venue, highlighting its role as a ‘meeting place’ where borders, ecosystems, and diverse stakeholders converge. "This location symbolises the very essence of our conference," Prof Klopper stated, "a space where we transcend boundaries to address the challenges facing our mountain regions".

Welcome statements were also delivered by Sara Manuelli from the Mountain Partnership, Ambassador Mirko Manzoni of the Embassy of Switzerland in South Africa, and Ndapanda Kanime, who represented the Southern African Development Community (SADC).

Dr Kelly Cerialo, representing UNESCO – the patron of SAMC 2025 – delivered a welcoming address that highlighted the organisation's commitment to supporting mountain research and conservation. The official opening was conducted by Leluma Matooane, representative of the Department of Science, Technology and Innovation.

Sharing insightful books, film, and mountains

Following the official opening, delegates attended a plenary keynote address by Dr Willem Daffue, which delved into critical aspects of mountain research. The morning session also featured a series of book launches, celebrating new publications from ARU and GLOMOS, including Sustainable Futures in Southern Africa's Mountains, Safeguarding Mountain Social-Ecological Systems, A scientific bibliography of the Waterberg, Makgabeng plateau, Blouberg, Soutpansberg and adjacent areas, and Christopher R Conz’s Environment, Knowledge, and Injustice in Lesotho: The Poverty of Progress.

Monday 17 March 2025 will be etched in the annals of Southern African mountain research and storytelling as the documentary film, Qwaqwa: Place of Barriers and Bridges, premiered to a captivated audience at the Second Southern African Mountain Conference (SAMC 2025). Hosted against the breathtaking backdrop of the central Maloti-Drakensberg, the film’s release marked a powerful moment of reflection and a catalyst for crucial dialogue.

Executive produced by Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the University of the Free State (UFS), and Prof Jared McDonald, Qwaqwa: Place of Barriers and Bridges offers a poignant and unflinching look at the complex social and environmental realities of the Qwaqwa region. The film, screened on the conference's opening day, served as a compelling visual narrative bridging academic discourse with the lived experiences of mountain communities.

Dialogue, networking, conference continues

Delegates, researchers, and stakeholders from across the globe witnessed the film's debut, recognising its significant contribution to understanding the challenges and opportunities within the Maloti-Drakensberg landscape. The film's premiere was not merely a screening; it was a watershed moment, sparking immediate conversations about the interplay between human activity and the fragile ecosystems of the region.

The film's release at SAMC 2025 highlighted the conference's commitment to fostering interdisciplinary dialogue and bridging the gap between research and real-world impact. By showcasing the human stories embedded in the mountains, Qwaqwa: Place of Barriers and Bridges provided a powerful emotional anchor to the conference's broader discussions on sustainability, conservation, and community resilience.

This premiere will undoubtedly resonate far beyond the conference halls, leaving an indelible mark on the collective understanding of the Maloti-Drakensberg region. The film's legacy will be one of inspiration, prompting further research, advocacy, and collaborative action to safeguard these vital mountain ecosystems for generations to come. The day will go down in history as a moment where film and scholarship intersected to illuminate the heart of the mountains.

The day concluded with a meet-and-greet hosted by the UFS Office for International Affairs, fostering networking and further collaboration among delegates.

The conference continues for the rest of the week, with a full programme of presentations, workshops, and field excursions. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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