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19 March 2025 | Story Precious Shamase | Photo Andre Damons
SAMC 2025
Prof Jared McDonald, Associate Professor in the Department of History; Dr Grey Magaiza, Senior Lecturer: Centre for Gender and Africa Studies, and Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the University of the Free State (UFS).

The Second Southern African Mountain Conference (SAMC 2025) commenced on Monday, 17 March amid a tangible sense of anticipation and a collaborative spirit at the Champagne Sports Resort, nestled in the heart of the Maloti-Drakensberg. Delegates from across the region and beyond gathered, setting the stage for a week of insightful discussions and collaborative exploration under the theme, ‘Southern African Mountains – Overcoming Boundaries and Barriers.’

Hosted by the University of the Free State (UFS) and its Afromontane Research Unit (ARU), the conference opened with a series of welcome statements that emphasised the global significance of mountain ecosystems. Prof Ralph Clark, SAMC 2025 Conference Chair and Session Chair, initiated the proceedings, setting the tone for a conference focused on actionable solutions.

Collaboration transcends mountain borders

The global reach of the conference was immediately evident, with welcome addresses from key partners. Prof Roland Psenner, President of Eurac Research – speaking on behalf of the Global Mountain Safeguard Programme (GLOMOS) – highlighted the importance of international collaboration. Alex Hickman, Chairman of the African Mountain Research Foundation (AMRF), highlighted the critical work being done on the ground. Notably, a recorded message from Prince Harry, Duke of Sussex, in support of the AMRF resonated with attendees, further amplifying the message of the conference.

Prof Hester C. Klopper, Vice-Chancellor and Principal of the UFS – speaking on behalf of the ARU – stressed the significance of the venue, highlighting its role as a ‘meeting place’ where borders, ecosystems, and diverse stakeholders converge. "This location symbolises the very essence of our conference," Prof Klopper stated, "a space where we transcend boundaries to address the challenges facing our mountain regions".

Welcome statements were also delivered by Sara Manuelli from the Mountain Partnership, Ambassador Mirko Manzoni of the Embassy of Switzerland in South Africa, and Ndapanda Kanime, who represented the Southern African Development Community (SADC).

Dr Kelly Cerialo, representing UNESCO – the patron of SAMC 2025 – delivered a welcoming address that highlighted the organisation's commitment to supporting mountain research and conservation. The official opening was conducted by Leluma Matooane, representative of the Department of Science, Technology and Innovation.

Sharing insightful books, film, and mountains

Following the official opening, delegates attended a plenary keynote address by Dr Willem Daffue, which delved into critical aspects of mountain research. The morning session also featured a series of book launches, celebrating new publications from ARU and GLOMOS, including Sustainable Futures in Southern Africa's Mountains, Safeguarding Mountain Social-Ecological Systems, A scientific bibliography of the Waterberg, Makgabeng plateau, Blouberg, Soutpansberg and adjacent areas, and Christopher R Conz’s Environment, Knowledge, and Injustice in Lesotho: The Poverty of Progress.

Monday 17 March 2025 will be etched in the annals of Southern African mountain research and storytelling as the documentary film, Qwaqwa: Place of Barriers and Bridges, premiered to a captivated audience at the Second Southern African Mountain Conference (SAMC 2025). Hosted against the breathtaking backdrop of the central Maloti-Drakensberg, the film’s release marked a powerful moment of reflection and a catalyst for crucial dialogue.

Executive produced by Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the University of the Free State (UFS), and Prof Jared McDonald, Qwaqwa: Place of Barriers and Bridges offers a poignant and unflinching look at the complex social and environmental realities of the Qwaqwa region. The film, screened on the conference's opening day, served as a compelling visual narrative bridging academic discourse with the lived experiences of mountain communities.

Dialogue, networking, conference continues

Delegates, researchers, and stakeholders from across the globe witnessed the film's debut, recognising its significant contribution to understanding the challenges and opportunities within the Maloti-Drakensberg landscape. The film's premiere was not merely a screening; it was a watershed moment, sparking immediate conversations about the interplay between human activity and the fragile ecosystems of the region.

The film's release at SAMC 2025 highlighted the conference's commitment to fostering interdisciplinary dialogue and bridging the gap between research and real-world impact. By showcasing the human stories embedded in the mountains, Qwaqwa: Place of Barriers and Bridges provided a powerful emotional anchor to the conference's broader discussions on sustainability, conservation, and community resilience.

This premiere will undoubtedly resonate far beyond the conference halls, leaving an indelible mark on the collective understanding of the Maloti-Drakensberg region. The film's legacy will be one of inspiration, prompting further research, advocacy, and collaborative action to safeguard these vital mountain ecosystems for generations to come. The day will go down in history as a moment where film and scholarship intersected to illuminate the heart of the mountains.

The day concluded with a meet-and-greet hosted by the UFS Office for International Affairs, fostering networking and further collaboration among delegates.

The conference continues for the rest of the week, with a full programme of presentations, workshops, and field excursions. 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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