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15 May 2025 | Story Precious Shamase | Photo Teboho Mositi
From right to left : Prof Aliza le Roux, Dr Regret Sunge, Prof Jared McDonald and Dr Calvin Mudzingiri.

The University of the Free State Qwaqwa Campus is celebrating a significant boost to its academic and research standing with the recent achievement of National Research Foundation (NRF) ratings by several esteemed academics. These ratings not only recognise the individual accomplishments and impact of these researchers but also underscore the campus' commitment to Vision 130 and the university's overarching strategy for academic and research excellence.

The Deputy Vice-Chancellor: Research and Internationalisation, Prof Vasu Reddy, explained the ratings, saying, “Ratings embody high ideals and recognition of scientific merit and impact in a knowledge-intensive economy, aligned with the UFS’ aspirations.”

Prof Jared McDonald, Assistant Dean of the Faculty of The Humanities, Dr Calvin Mudzingiri, Assistant Dean of the Faculty of Economic and Management Sciences, and Prof Richard Ocaya from the Department of Physics have all been awarded C2 ratings, signifying that they are established researchers with considerable international recognition for the quality and impact of their research outputs. This level of recognition highlights their consistent contribution to their respective fields and positions them as key players within the global research landscape.

Building on this impressive achievement, Prof Aliza le Roux, Assistant Dean of the Faculty of Natural and Agricultural Sciences, has attained a C1 rating, indicating that she is a leading international researcher recognised for the high quality and impact of her recent research outputs. This prestigious rating stresses Prof Le Roux's significant contributions and her standing as a prominent figure in her area of expertise.

Adding to the growing cadre of research talent on the Qwaqwa Campus, Dr Nthatisi Nyembe, Lecturer in the Department of Zoology and Entomology, and Dr Victor Gwande – Senior Lecturer in the Department of History – have both received Y1 ratings. Dr Regret Sunge, Lecturer in the Department of Economics and Finance within the Faculty of Economic and Management Sciences, has received the NRF Y2 rating for the period 1 January 2025 to 31 December 2030. This rating is awarded to promising young researchers who have demonstrated the potential to establish themselves as researchers with strong international recognition within five years after obtaining their doctorates. These Y1 ratings signal a bright future for research on the campus, highlighting the emergence of a new generation of impactful scholars.

NRF ratings are a crucial benchmark within the South African academic and research sector. They provide a peer-review assessment of the quality and impact of researchers' work, lending credibility and prestige to both the individual and their institution. For academics, a strong NRF rating can enhance their research collaborations, funding opportunities, and overall academic standing. For the institution, a growing number of rated researchers reflects a vibrant research environment and contributes to its reputation as a leading centre of knowledge production.

These achievements align directly with the UFS' Vision 130, which aims to elevate the university's academic and research profile, fostering a culture of innovation and impactful scholarship. The success of these Qwaqwa Campus academics demonstrates the tangible progress being made towards realising this vision and strengthening the university's strategic goals in academic and research excellence.

The UFS is committed to nurturing and supporting its academics in their research endeavours. Initiatives such as the Future Professoriate Programme and the Emerging Scholars Advancement Programme (ESAP) play a vital role in providing mentorship, resources, and opportunities for academics to develop their research careers and achieve their full potential. The recent NRF ratings are a testament to the effectiveness of these support structures and the dedication of the academics on the Qwaqwa Campus.

The University of the Free State proudly celebrates the accomplishments of Prof McDonald, Dr Mudzingiri, Prof Ocaya, Prof Le Roux, Dr Nyembe, Dr Gwande, and Regret Sunge. Their success is a source of inspiration for the entire university community and reaffirms the Qwaqwa Campus' growing prominence as a hub of impactful research.

In his congratulatory remarks, Prof Reddy said: “Our colleagues’ ratings confirm their dedicated and sterling work in advancing research and innovation. It is commendable to also see academic leaders in professional support being beacons to inspire others.”

He further commented: “We value your hard work and determination. Congratulations, you make us proud as a university. You inspire us all to follow you and we support you in reaching our research-intensive goals. We are confident that your ratings will inspire you, personally and professionally – as well as other colleagues – to grow further. Your efforts will help us as we move to new heights,” Prof Reddy concluded.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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