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06 May 2025 | Story Andre Damons | Photo Supplied
Prof Nyaga
Prof Martin Nyaga at the UFS-NGS Unit sequencing room giving a talk on the Illumina NextSeq 2000 with the P3 flow cell in hand.

The University of the Free State – Next Generation Sequencing (UFS-NGS) Unit hosted a pioneering scholarly engagement initiative for Grade 11 learners from nine secondary schools in Bloemfontein. The three-day event with the theme "Frontiers of Discovery: Illuminating the Impact of Genomics in Science outreach programme” marked the first comprehensive genomics science outreach initiative in the Faculty Health Sciences.

Coordinated by Prof Martin Nyaga, Head of the UFS-NGS Unit, the programme bridged the longstanding gap through practical NGS exposure and ignited a passion for Science, Technology, Engineering, and Mathematics (STEM) by inspiring the next generation of genomic innovators using combined interactive lectures, laboratory demonstrations, career talks, and hands-on workshops. This allowed learners to directly engage with cutting-edge scientific techniques and genomic technologies, especially the scientific and evolutionally impact of Polymerase Chain Reaction (PCR) and NGS.

The initiative engaged selected Grade 11 learners from the nine schools: Brebner, Ikaelelo and Vulamasango (day 1), Atlehang, Castle Bridge School and Kaelang (day 2) and Eunice, Navalsig, and Lekhulong (day 3).

“This outreach programme marks a significant milestone in community-based genomics education in South Africa by offering high school learners the opportunity to engage with modern genomic sciences before making career decisions. The initiative particularly aimed to nurture future scientists and diversify the country’s STEM talent pipeline.

“This historic programme bridged gaps in scientific literacy and diversity in the Free State and concluded each day with a genomics quiz competition, which tested the participant’s newly acquired knowledge/exposure and provided a fun competitive learning opportunity. Six quiz winners across the three days received special prizes, and all students were awarded certificates of participation,” says Prof Nyaga.

 

Hands-on exploration and NHLS virology laboratory tour

The training was held at the UFS-NGS Unit in the School of Biomedical Sciences and at the NHLS Virology laboratories, School of Pathology, Faculty of Health Sciences. Each attending secondary school was represented by five Grade 11 learners and a life science’s educator. Each day, 15 learners and three educators observed hands-on practicals, including DNA extraction, PCR, gel electrophoresis, and DNA library preparation for sequencing on platforms such as Illumina MiSeq and NextSeq 2000.

Guided by the UFS-NGS Unit’s team members; Dr Milton Mogotsi, Hlengiwe Sondlane, Mbali Ncube, Nkosazana Shange, Somila Nazo, Sesiyanda Maseko, Surprise Baloyi, Manyi Eyong and Mamello Maku, the learners were exposed to how DNA is extracted and visualised, how the PCR machine works and how DNA libraries are prepared and sequenced.

Furthermore, a guided laboratory tour of the Virology laboratories at the NHLS was provided by Khauhelo Mafa which offered the leaners the opportunity to observe, diagnostic and molecular workflows in action, resulting in a real-time glimpse into world-class medical research and diagnostics, fuelling curiosity about the role of advanced genomics science in disease control.

 

Inspiration through expert talks

The learners were also inspired by talks from Prof Chris Viljoen, Head of the School of Biomedical Sciences, Prof Zinhle Makatini, Associate Professor and Head of Division of Virology, School of Pathology, and Dr Claudia Ntsapi, Senior Lecturer and researcher in the Department of Basic Medical Sciences at the UFS. Prof Viljoen highlighted the role of science in transforming lives and improving life expectancy, while Prof Makatini gave candid reflections on her professional journey, particularly how she pursued Medical Virology through unwavering determination and excelled to become among the pioneer women specialists in the field in South Africa. Dr Ntsapi inspired the audience with her perseverance from her humble beginnings to earning a PhD in Neurophysiological Sciences against all odds.

The speakers also delivered compelling presentations on the applications of genomics in medicine (e.g.), personalised cancer treatments), public health (e.g.), tracking HIV and COVID-19), agriculture (e.g.), resilient crops), and environmental science (e.g.), ecosystem protection), which resonated well with the learners, educators and the UFS-NGS team. A presentation on diverse career options available at the UFS Faculty of Health Sciences was further provided by Angelique Carson-Porter, a UFS representative from the Department of Nutrition & Dietetics. Her talk on different career pathways in Health Sciences broaden the learners’ horizons, fostering future aspirations.

Dr Emmanuel Ogunbayo, Dr Mogotsi, Thabisa Mpaxa, Nkosazana Shange and Eyong Manyi shared their personal career journey to be at the UFS-NGS Unit, offering advice on academic experiences and opportunities within genomics, bioinformatics, and biotechnology, while answering scholarship queries.

“The career talk opened my eyes. I’m now aiming for a biotechnology degree!” said Neliswa Thwala, a learner from Navalsig CS/S.

Following the enthusiastic response and tangible outcomes of this programme, the UFS-NGS Unit is committed to expanding this initiative, with plans to introduce similar events to other schools and developing sustained mentorship opportunities for learners interested in pursuing genomics-related careers. The UFS-NGS Unit further invites interested partners, sponsors, and stakeholders to collaborate in future outreach and capacity-building programmes to continue bridging the genomics education gap in Africa.

 

Inspire the next generation

Prof. Nyaga’s closing remarks highlighted the learners’ potential to shape the ‘omics’ workforce and stated the intention of the organising committee to expand the mentorship programmes, fostering a vibrant STEM pipeline. “This initiative represents our vision to make genomics accessible and inspire the next generation of African scientists.”

The success of this programme was driven by the UFS-NGS Unit team and was supported by Distribution Platform in Omics (DIPLOMICS).

  • For more information about the UFS-NGS Unit or future outreach programmes, please visit our website. Further pictures from the event are also available via our website.

News Archive

Internationally acclaimed academic applauded on Africa Day
2011-06-02

 
 Prof. Ali Mazrui, an internationally acclaimed and renowned academic.

One of the world’s top academics was given a warm welcome in the rather cold Free State recently.

Prof. Ali Mazrui, an internationally acclaimed and renowned academic, visited us as part of our Africa Day celebrations as arranged by the Centre for Africa Studies. He delivered a keynote address, entitled ‘Pro-democracy uprisings in an African experience: from Sharpeville to Benghazi.’

A festive atmosphere and the sound of drums welcomed this intellectual giant as well as other delegates upon their arrival at the CR Swart Auditorium on our Bloemfontein Campus. Some of the delegates who attended the Africa Day Celebrations, included: Mr Tom Amolo, High Commissioner from the Republic of Kenya; Mr Dan Kgothule, MEC of Arts and Culture in the province; Prof. Jeff and Dr Carla Ramsdell, visitors from America; Dr Allan Boesak and Prof. Nicky Morgan, Vice-Rector: Operations.

Prof. Frederick Fourie, former Vice-Chancellor and Rector of our university, also attended the celebrations, as did some scholars from neighboring schools.

Welcoming Prof. Mazrui, Prof. Jonathan Jansen, Vice-Chancellor and Rector of our university, quipped that he was relieved the world had not ended the previous weekend as was predicted, because he was looking forward to listening to such a renowned intellectual.

Prof. Lucius Botes, Dean of Humanities, followed Prof. Jansen at the podium. He said the ability to go from following a bridging course to being one of the top 100 intellectuals in the world, indeed distinguishes Prof. Mazrui as an exceptional academic. This intellectual is, among others, an Albert Luthuli Professor at the University of Jos, Nigeria and Andrew D. Professor Emeritus and Senior Scholar in Africana Studies at Cornell University.

In his introduction, Prof. Mazrui said he feels honored and flattered by this opportunity. He proceeded by referring to the history of Africa Day and added that he would rather prefer an Africa Week to an Africa Day to ensure that everybody has the opportunity to celebrate the continent.

He sang the praises of South Africa, as almost every other African country which attained liberation from European colonial rule in the 20th century, has been unable to maintain its democratic order beyond its first decade of independence.

“The Republic of South Africa, on the other hand, liberated Nelson Mandela in 1990, held its first democratic election in 1994, and already has its third president. Nearly two decades after Apartheid, South Africa has not outlawed opposition parties, or experienced a military coup, or permitted the Head of State to govern the country as a dictator.”

In his speech he compared the uprisings in Sharpeville during 1960 and Soweto during 1976 with the more recent pro-democracy uprisings in North Africa, based on the role that weapons and the lack thereof, as well as the youth and women played in the respective cases.

He concluded by saying the uprisings in Tunisia and Egypt have already resulted in ousting dictators who had been entrenched in power for decades, adding that in Libya a third dictator’s future is on the line. “Never in the history of the Arabs have there been so many popular uprisings which seem to be inspired neither by Islam nor by anti-imperialism, but in the quest for liberal reforms. Half a century earlier in Sharpeville and Soweto, South Africans experienced their own political awakening.”

Prof. Kwandiwe Kondlo, Director of the Centre for Africa Studies, closed the event with a word of thanks to the American academic and his wife, guests and attendees. He said discussions prior to the event revealed that more research has to be done regarding gender issues on the continent.

Prof. Mazrui also participated in conversations at the institute and a media briefing which was hosted earlier the day.

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