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UFS-NGS UNIT engages high school learners in pioneering step toward a genomic education

06 May 2025 | Story Andre Damons | Photo Supplied

Prof Nyaga — Prof Martin Nyaga at the UFS-NGS Unit sequencing room giving a talk on the Illumina NextSeq 2000 with the P3 flow cell in hand.

The University of the Free State – Next Generation Sequencing (UFS-NGS) Unit hosted a pioneering scholarly engagement initiative for Grade 11 learners from nine secondary schools in Bloemfontein. The three-day event with the theme "Frontiers of Discovery: Illuminating the Impact of Genomics in Science outreach programme” marked the first comprehensive genomics science outreach initiative in the Faculty Health Sciences.

Coordinated by Prof Martin Nyaga, Head of the UFS-NGS Unit, the programme bridged the longstanding gap through practical NGS exposure and ignited a passion for Science, Technology, Engineering, and Mathematics (STEM) by inspiring the next generation of genomic innovators using combined interactive lectures, laboratory demonstrations, career talks, and hands-on workshops. This allowed learners to directly engage with cutting-edge scientific techniques and genomic technologies, especially the scientific and evolutionally impact of Polymerase Chain Reaction (PCR) and NGS.

The initiative engaged selected Grade 11 learners from the nine schools: Brebner, Ikaelelo and Vulamasango (day 1), Atlehang, Castle Bridge School and Kaelang (day 2) and Eunice, Navalsig, and Lekhulong (day 3).

“This outreach programme marks a significant milestone in community-based genomics education in South Africa by offering high school learners the opportunity to engage with modern genomic sciences before making career decisions. The initiative particularly aimed to nurture future scientists and diversify the country’s STEM talent pipeline.

“This historic programme bridged gaps in scientific literacy and diversity in the Free State and concluded each day with a genomics quiz competition, which tested the participant’s newly acquired knowledge/exposure and provided a fun competitive learning opportunity. Six quiz winners across the three days received special prizes, and all students were awarded certificates of participation,” says Prof Nyaga.

Hands-on exploration and NHLS virology laboratory tour

The training was held at the UFS-NGS Unit in the School of Biomedical Sciences and at the NHLS Virology laboratories, School of Pathology, Faculty of Health Sciences. Each attending secondary school was represented by five Grade 11 learners and a life science’s educator. Each day, 15 learners and three educators observed hands-on practicals, including DNA extraction, PCR, gel electrophoresis, and DNA library preparation for sequencing on platforms such as Illumina MiSeq and NextSeq 2000.

Guided by the UFS-NGS Unit’s team members; Dr Milton Mogotsi, Hlengiwe Sondlane, Mbali Ncube, Nkosazana Shange, Somila Nazo, Sesiyanda Maseko, Surprise Baloyi, Manyi Eyong and Mamello Maku, the learners were exposed to how DNA is extracted and visualised, how the PCR machine works and how DNA libraries are prepared and sequenced.

Furthermore, a guided laboratory tour of the Virology laboratories at the NHLS was provided by Khauhelo Mafa which offered the leaners the opportunity to observe, diagnostic and molecular workflows in action, resulting in a real-time glimpse into world-class medical research and diagnostics, fuelling curiosity about the role of advanced genomics science in disease control.

Inspiration through expert talks

The learners were also inspired by talks from Prof Chris Viljoen, Head of the School of Biomedical Sciences, Prof Zinhle Makatini, Associate Professor and Head of Division of Virology, School of Pathology, and Dr Claudia Ntsapi, Senior Lecturer and researcher in the Department of Basic Medical Sciences at the UFS. Prof Viljoen highlighted the role of science in transforming lives and improving life expectancy, while Prof Makatini gave candid reflections on her professional journey, particularly how she pursued Medical Virology through unwavering determination and excelled to become among the pioneer women specialists in the field in South Africa. Dr Ntsapi inspired the audience with her perseverance from her humble beginnings to earning a PhD in Neurophysiological Sciences against all odds.

The speakers also delivered compelling presentations on the applications of genomics in medicine (e.g.), personalised cancer treatments), public health (e.g.), tracking HIV and COVID-19), agriculture (e.g.), resilient crops), and environmental science (e.g.), ecosystem protection), which resonated well with the learners, educators and the UFS-NGS team. A presentation on diverse career options available at the UFS Faculty of Health Sciences was further provided by Angelique Carson-Porter, a UFS representative from the Department of Nutrition & Dietetics. Her talk on different career pathways in Health Sciences broaden the learners’ horizons, fostering future aspirations.

Dr Emmanuel Ogunbayo, Dr Mogotsi, Thabisa Mpaxa, Nkosazana Shange and Eyong Manyi shared their personal career journey to be at the UFS-NGS Unit, offering advice on academic experiences and opportunities within genomics, bioinformatics, and biotechnology, while answering scholarship queries.

“The career talk opened my eyes. I’m now aiming for a biotechnology degree!” said Neliswa Thwala, a learner from Navalsig CS/S.

Following the enthusiastic response and tangible outcomes of this programme, the UFS-NGS Unit is committed to expanding this initiative, with plans to introduce similar events to other schools and developing sustained mentorship opportunities for learners interested in pursuing genomics-related careers. The UFS-NGS Unit further invites interested partners, sponsors, and stakeholders to collaborate in future outreach and capacity-building programmes to continue bridging the genomics education gap in Africa.

Inspire the next generation

Prof. Nyaga’s closing remarks highlighted the learners’ potential to shape the ‘omics’ workforce and stated the intention of the organising committee to expand the mentorship programmes, fostering a vibrant STEM pipeline. “This initiative represents our vision to make genomics accessible and inspire the next generation of African scientists.”

The success of this programme was driven by the UFS-NGS Unit team and was supported by Distribution Platform in Omics (DIPLOMICS).

For more information about the UFS-NGS Unit or future outreach programmes, please visit our website. Further pictures from the event are also available via our website.

News Archive

Lecture by Judge Albie Sachs: ‘Sites of memory, sites of conscience’

2015-03-23

Judge Albie Sachs

Human rights activist and former Constitutional Court Judge, Albie Sachs, will deliver a public lecture on the Bloemfontein Campus. The topic of his discussion will be ‘Sites of memory, sites of conscience’. This lecture will form part of a series that focuses on how the creative arts represent trauma and memory – and how these representations may ultimately pave the way to healing historical wounds.

The details of the event are:
Date: Thursday 26 March 2015
Time: 12:30
Venue: Albert Wessels Auditorium, Bloemfontein Campus
RSVP: Jo-Anne Naidoo at Naidooja@ufs.ac.za
A South African Sign Language interpreter will be present at the event.

Joining Judge Sachs on stage as respondent will be Dr Buhle Zuma, a young scholar and lecturer at the University of Cape Town's Psychology Department.

Expressing experiences of trauma
Judge Sachs is no stranger to the use of the arts as a way of expressing the inarticulable and overwhelming experiences of trauma. Targeted as an anti-apartheid freedom fighter, he lost his right arm and was blinded in one eye in a car bomb attack in 1988. As a judge of the Constitutional Court, he spearheaded conversations about the role of the arts in our constitutional democracy. This has led to the installation of some of the best artworks by South African artists at the Constitutional Court.

Vice-Chancellor’s Lecture Series on Trauma, Memory, and Representations of the Past
This lecture will launch of the Vice Chancellor’s Lecture Series on Trauma, Memory and Representations of the Past. It forms part of a five-year research project led by Prof Pumla Gobodo-Madikizela, funded by the Mellon Foundation. The event is hosted by the UFS Trauma, Forgiveness and Reconciliation Studies.

“One of the most remarkable aspects of trauma,” Prof Gobodo-Madikizela says, “is the loss of language, a moment of rupture that produces what some scholars have referred to as ‘speechless terror’. The arts, in all its forms – literary, performance, and visual – are a viable mechanism through which the unspeakable, traumatic past may be represented.”

These artistic forms of representing trauma are at the heart of this Vice-Chancellor’s Lecture Series. “We are interested not only in how experiences that transcend language are represented through the arts,” Prof Gobodo-Madikizela explains, “but also in probing the limits of trauma theory, and how the creative arts might be employed to bear witness in a way that may open up the possibility of healing.”

Dr Buhle Zuma
Former Mandela Rhodes scholar and one of the 2011 Mail & Guardian’s 200 Young South Africans, Dr Zuma is particularly interested in issues at the heart of our rainbow nation. His current research revolves around the question of freedom: what it means to be human for black people after centuries of dehumanisation, and the role of desire and fantasy in the political imagination of post-apartheid South Africa.

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