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UFS-NGS UNIT engages high school learners in pioneering step toward a genomic education

06 May 2025 | Story Andre Damons | Photo Supplied

Prof Nyaga — Prof Martin Nyaga at the UFS-NGS Unit sequencing room giving a talk on the Illumina NextSeq 2000 with the P3 flow cell in hand.

The University of the Free State – Next Generation Sequencing (UFS-NGS) Unit hosted a pioneering scholarly engagement initiative for Grade 11 learners from nine secondary schools in Bloemfontein. The three-day event with the theme "Frontiers of Discovery: Illuminating the Impact of Genomics in Science outreach programme” marked the first comprehensive genomics science outreach initiative in the Faculty Health Sciences.

Coordinated by Prof Martin Nyaga, Head of the UFS-NGS Unit, the programme bridged the longstanding gap through practical NGS exposure and ignited a passion for Science, Technology, Engineering, and Mathematics (STEM) by inspiring the next generation of genomic innovators using combined interactive lectures, laboratory demonstrations, career talks, and hands-on workshops. This allowed learners to directly engage with cutting-edge scientific techniques and genomic technologies, especially the scientific and evolutionally impact of Polymerase Chain Reaction (PCR) and NGS.

The initiative engaged selected Grade 11 learners from the nine schools: Brebner, Ikaelelo and Vulamasango (day 1), Atlehang, Castle Bridge School and Kaelang (day 2) and Eunice, Navalsig, and Lekhulong (day 3).

“This outreach programme marks a significant milestone in community-based genomics education in South Africa by offering high school learners the opportunity to engage with modern genomic sciences before making career decisions. The initiative particularly aimed to nurture future scientists and diversify the country’s STEM talent pipeline.

“This historic programme bridged gaps in scientific literacy and diversity in the Free State and concluded each day with a genomics quiz competition, which tested the participant’s newly acquired knowledge/exposure and provided a fun competitive learning opportunity. Six quiz winners across the three days received special prizes, and all students were awarded certificates of participation,” says Prof Nyaga.

Hands-on exploration and NHLS virology laboratory tour

The training was held at the UFS-NGS Unit in the School of Biomedical Sciences and at the NHLS Virology laboratories, School of Pathology, Faculty of Health Sciences. Each attending secondary school was represented by five Grade 11 learners and a life science’s educator. Each day, 15 learners and three educators observed hands-on practicals, including DNA extraction, PCR, gel electrophoresis, and DNA library preparation for sequencing on platforms such as Illumina MiSeq and NextSeq 2000.

Guided by the UFS-NGS Unit’s team members; Dr Milton Mogotsi, Hlengiwe Sondlane, Mbali Ncube, Nkosazana Shange, Somila Nazo, Sesiyanda Maseko, Surprise Baloyi, Manyi Eyong and Mamello Maku, the learners were exposed to how DNA is extracted and visualised, how the PCR machine works and how DNA libraries are prepared and sequenced.

Furthermore, a guided laboratory tour of the Virology laboratories at the NHLS was provided by Khauhelo Mafa which offered the leaners the opportunity to observe, diagnostic and molecular workflows in action, resulting in a real-time glimpse into world-class medical research and diagnostics, fuelling curiosity about the role of advanced genomics science in disease control.

Inspiration through expert talks

The learners were also inspired by talks from Prof Chris Viljoen, Head of the School of Biomedical Sciences, Prof Zinhle Makatini, Associate Professor and Head of Division of Virology, School of Pathology, and Dr Claudia Ntsapi, Senior Lecturer and researcher in the Department of Basic Medical Sciences at the UFS. Prof Viljoen highlighted the role of science in transforming lives and improving life expectancy, while Prof Makatini gave candid reflections on her professional journey, particularly how she pursued Medical Virology through unwavering determination and excelled to become among the pioneer women specialists in the field in South Africa. Dr Ntsapi inspired the audience with her perseverance from her humble beginnings to earning a PhD in Neurophysiological Sciences against all odds.

The speakers also delivered compelling presentations on the applications of genomics in medicine (e.g.), personalised cancer treatments), public health (e.g.), tracking HIV and COVID-19), agriculture (e.g.), resilient crops), and environmental science (e.g.), ecosystem protection), which resonated well with the learners, educators and the UFS-NGS team. A presentation on diverse career options available at the UFS Faculty of Health Sciences was further provided by Angelique Carson-Porter, a UFS representative from the Department of Nutrition & Dietetics. Her talk on different career pathways in Health Sciences broaden the learners’ horizons, fostering future aspirations.

Dr Emmanuel Ogunbayo, Dr Mogotsi, Thabisa Mpaxa, Nkosazana Shange and Eyong Manyi shared their personal career journey to be at the UFS-NGS Unit, offering advice on academic experiences and opportunities within genomics, bioinformatics, and biotechnology, while answering scholarship queries.

“The career talk opened my eyes. I’m now aiming for a biotechnology degree!” said Neliswa Thwala, a learner from Navalsig CS/S.

Following the enthusiastic response and tangible outcomes of this programme, the UFS-NGS Unit is committed to expanding this initiative, with plans to introduce similar events to other schools and developing sustained mentorship opportunities for learners interested in pursuing genomics-related careers. The UFS-NGS Unit further invites interested partners, sponsors, and stakeholders to collaborate in future outreach and capacity-building programmes to continue bridging the genomics education gap in Africa.

Inspire the next generation

Prof. Nyaga’s closing remarks highlighted the learners’ potential to shape the ‘omics’ workforce and stated the intention of the organising committee to expand the mentorship programmes, fostering a vibrant STEM pipeline. “This initiative represents our vision to make genomics accessible and inspire the next generation of African scientists.”

The success of this programme was driven by the UFS-NGS Unit team and was supported by Distribution Platform in Omics (DIPLOMICS).

For more information about the UFS-NGS Unit or future outreach programmes, please visit our website. Further pictures from the event are also available via our website.

News Archive

UFS celebrates Kagiso Trust’s 30 years of commitment to the empowerment of impoverished communities

2015-07-15

From the left are: MEC Tate Makgoe, Free State Department of Education; Busi Tshabalala, Thabo Mofutsanyana Education District Director; Dean Zwo Nevhutalu, Kagiso Trust Trustee and UFS Director of Community Engagement, Bishop, Billy Ramahlele.
Photo: ?Thabo Kessah

Future sustainable partnerships in education will survive only if all partners are committed, honest, and transparent.

This is the view expressed by the Free State MEC for Education and UFS Council member, Tate Makgoe, during the panel discussion at the Qwaqwa Campus of the University of the Free State celebrating Kagiso Trust’s 30 years of commitment to the empowerment of impoverished communities. The topic was “The future partnership models for education in Africa”.

“Over the years, the partnership between the Free State Department of Education, the UFS, and Kagiso Trust has helped to expose the potential in our mainly rural children in the Qwaqwa area of the Thabo Mofutsanyana district,” said Makgoe.

”When we started in 2009, the matric pass rate in the district was 64%, and this rose to 87% in 2014. In Qwaqwa alone, we have managed to build 51 computer and 26 physical sciences laboratories. It was these laboratories that enabled the Free State to be the best performing province in the Physical Sciences in 2013,” added Makgoe.

“None of these achievements would have been possible if all the partners had not been committed to the course. Partnerships built on honesty and transparency are the best model, which we hope to export to other provinces and, indeed, countries,” Makgoe said.

Representing the UFS on the panel was the Director of Community Engagement, Bishop Billy Ramahlele, who added that collaborations can be successful only if the leadership was exemplary.

“As the university, we have had many collaboration with various government departments, and great strides have been achieved only with the Department of Education under the leadership of MEC Makgoe,” said Ramahlele.

”With the MEC on board, the UFS ended up dedicating its South Campus in Bloemfontein to supporting Free State schools. We now have 70 schools that benefit from live television broadcasts of lessons by some of our outstanding academics. This also enables our best academics to make a valued contribution to empowering our teachers. It also allows the university to maximise scarce resources to attain social cohesion,” he said.

In his remarks, Kagiso Trust Trustee, Dean Zwo Nevhutalu, said that Kagiso Trust was looking forward to continue working with its partners to maximise outcomes through limited resources.

“Kagiso Trust will continue to work with the poor and the marginalised and there is no better partner than the government itself. The government provides basic services, and education is one of them. This allows us to be innovative and not just dump books and equipment at schools because we are forced to by our corporate social investment obligations. Therefore, we challenge the government also to be innovative in building a sustainable future partnership model in education,” he said.

Among the dignitaries attending the panel discussion were Kagiso Trust Chairman, Dr Frank Chikane, and the late Dr Beyers Naude’s family.

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