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UFS-NGS UNIT engages high school learners in pioneering step toward a genomic education

06 May 2025 | Story Andre Damons | Photo Supplied

Prof Nyaga — Prof Martin Nyaga at the UFS-NGS Unit sequencing room giving a talk on the Illumina NextSeq 2000 with the P3 flow cell in hand.

The University of the Free State – Next Generation Sequencing (UFS-NGS) Unit hosted a pioneering scholarly engagement initiative for Grade 11 learners from nine secondary schools in Bloemfontein. The three-day event with the theme "Frontiers of Discovery: Illuminating the Impact of Genomics in Science outreach programme” marked the first comprehensive genomics science outreach initiative in the Faculty Health Sciences.

Coordinated by Prof Martin Nyaga, Head of the UFS-NGS Unit, the programme bridged the longstanding gap through practical NGS exposure and ignited a passion for Science, Technology, Engineering, and Mathematics (STEM) by inspiring the next generation of genomic innovators using combined interactive lectures, laboratory demonstrations, career talks, and hands-on workshops. This allowed learners to directly engage with cutting-edge scientific techniques and genomic technologies, especially the scientific and evolutionally impact of Polymerase Chain Reaction (PCR) and NGS.

The initiative engaged selected Grade 11 learners from the nine schools: Brebner, Ikaelelo and Vulamasango (day 1), Atlehang, Castle Bridge School and Kaelang (day 2) and Eunice, Navalsig, and Lekhulong (day 3).

“This outreach programme marks a significant milestone in community-based genomics education in South Africa by offering high school learners the opportunity to engage with modern genomic sciences before making career decisions. The initiative particularly aimed to nurture future scientists and diversify the country’s STEM talent pipeline.

“This historic programme bridged gaps in scientific literacy and diversity in the Free State and concluded each day with a genomics quiz competition, which tested the participant’s newly acquired knowledge/exposure and provided a fun competitive learning opportunity. Six quiz winners across the three days received special prizes, and all students were awarded certificates of participation,” says Prof Nyaga.

Hands-on exploration and NHLS virology laboratory tour

The training was held at the UFS-NGS Unit in the School of Biomedical Sciences and at the NHLS Virology laboratories, School of Pathology, Faculty of Health Sciences. Each attending secondary school was represented by five Grade 11 learners and a life science’s educator. Each day, 15 learners and three educators observed hands-on practicals, including DNA extraction, PCR, gel electrophoresis, and DNA library preparation for sequencing on platforms such as Illumina MiSeq and NextSeq 2000.

Guided by the UFS-NGS Unit’s team members; Dr Milton Mogotsi, Hlengiwe Sondlane, Mbali Ncube, Nkosazana Shange, Somila Nazo, Sesiyanda Maseko, Surprise Baloyi, Manyi Eyong and Mamello Maku, the learners were exposed to how DNA is extracted and visualised, how the PCR machine works and how DNA libraries are prepared and sequenced.

Furthermore, a guided laboratory tour of the Virology laboratories at the NHLS was provided by Khauhelo Mafa which offered the leaners the opportunity to observe, diagnostic and molecular workflows in action, resulting in a real-time glimpse into world-class medical research and diagnostics, fuelling curiosity about the role of advanced genomics science in disease control.

Inspiration through expert talks

The learners were also inspired by talks from Prof Chris Viljoen, Head of the School of Biomedical Sciences, Prof Zinhle Makatini, Associate Professor and Head of Division of Virology, School of Pathology, and Dr Claudia Ntsapi, Senior Lecturer and researcher in the Department of Basic Medical Sciences at the UFS. Prof Viljoen highlighted the role of science in transforming lives and improving life expectancy, while Prof Makatini gave candid reflections on her professional journey, particularly how she pursued Medical Virology through unwavering determination and excelled to become among the pioneer women specialists in the field in South Africa. Dr Ntsapi inspired the audience with her perseverance from her humble beginnings to earning a PhD in Neurophysiological Sciences against all odds.

The speakers also delivered compelling presentations on the applications of genomics in medicine (e.g.), personalised cancer treatments), public health (e.g.), tracking HIV and COVID-19), agriculture (e.g.), resilient crops), and environmental science (e.g.), ecosystem protection), which resonated well with the learners, educators and the UFS-NGS team. A presentation on diverse career options available at the UFS Faculty of Health Sciences was further provided by Angelique Carson-Porter, a UFS representative from the Department of Nutrition & Dietetics. Her talk on different career pathways in Health Sciences broaden the learners’ horizons, fostering future aspirations.

Dr Emmanuel Ogunbayo, Dr Mogotsi, Thabisa Mpaxa, Nkosazana Shange and Eyong Manyi shared their personal career journey to be at the UFS-NGS Unit, offering advice on academic experiences and opportunities within genomics, bioinformatics, and biotechnology, while answering scholarship queries.

“The career talk opened my eyes. I’m now aiming for a biotechnology degree!” said Neliswa Thwala, a learner from Navalsig CS/S.

Following the enthusiastic response and tangible outcomes of this programme, the UFS-NGS Unit is committed to expanding this initiative, with plans to introduce similar events to other schools and developing sustained mentorship opportunities for learners interested in pursuing genomics-related careers. The UFS-NGS Unit further invites interested partners, sponsors, and stakeholders to collaborate in future outreach and capacity-building programmes to continue bridging the genomics education gap in Africa.

Inspire the next generation

Prof. Nyaga’s closing remarks highlighted the learners’ potential to shape the ‘omics’ workforce and stated the intention of the organising committee to expand the mentorship programmes, fostering a vibrant STEM pipeline. “This initiative represents our vision to make genomics accessible and inspire the next generation of African scientists.”

The success of this programme was driven by the UFS-NGS Unit team and was supported by Distribution Platform in Omics (DIPLOMICS).

For more information about the UFS-NGS Unit or future outreach programmes, please visit our website. Further pictures from the event are also available via our website.

News Archive

UFS hosts first SA Digital Sky Academy at the Naval Hill Planetarium

2015-10-02

From the left are: Prof Neil Heideman
(Dean: Faculty of Natural and Agricultural Sciences, UFS),
Jack White (Director: Sky-Skan Oceania),
Dr Michelle Cluver (Department of Astronomy, University of the Western Cape),
Martin Ratcliffe (Director: Professional Development, Sky-Skan).
Photo: Mart-Mari Duvenhage

South Africa hosts some of the world’s largest telescopes, and won the bid to co-host the SKA recently. So it’s not surprising that there is unprecedented interest in Astronomy in our country. Astronomy is seen as a gateway subject that attracts people to the sciences, while planetariums help to make Astronomy accessible to millions of people. Digital planetariums are especially powerful teaching tools because they are versatile, offer an immersive experience, and explain and illustrate three-dimensional concepts effectively. On the other hand, scientists, are eager to exploit a digital planetarium’s potential to represent and explore data visually, whether the data relate to medicine, astronomy, chemistry, the environment, or other fields of research.

The four-day ‘Digital Sky Academy’ (DSA) presented at the Naval Hill Planetarium in Bloemfontein from 18 - 22 September 2015 was an opportunity to offer training and first-hand experience of digital planetarium technology to representatives from other centres in South Africa. The Department of Physics at the University of the Free State (UFS) was the host of this event.

The Department of Science and Technology has designated the Naval Hill Planetarium as the South African hub for the training of digital planetarium presenters and operators. In addition to attracting interest from scientists and future planetarium operators and presenters, the DSA workshop provided an invaluable opportunity for our presenters to hone their skills.

A number of experienced and distinguished people attended the workshop. Among them was Dr Mark SubbaRao from Chicago in the United States, who shared information on data visualisation techniques used in the Adler Planetarium. Jack White, Director of Sky-Skan, one of the few companies that provide digital technology for planetariums throughout the world, coordinated the event in partnership with Prof Matie Hoffman from the Department of Physics at the UFS.

Jack travelled from Melbourne in Australia to oversee the workshop. Two Sky-Skan colleagues from the United States, Martin Weiss and Martin Ratcliffe, were on hand to share their expertise on digital planetarium hardware and software. The workshop programme included Skype conference calls with other US-based planetarium experts. Amongst the delegates to the DSA representatives from the SKA, the Iziko Museum, and five South Africa universities. They were here to gain experience, explore the capacity of the digital facility, and share ideas on future collaboration.

During the workshop, a public lecture was held on 19 September. Dr Michelle Cluver from the University of the Western Cape gave a presentation entitled, ‘More than the eye can see: the significance of infrared light in Astronomy.’

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