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UFS-NGS UNIT engages high school learners in pioneering step toward a genomic education

06 May 2025 | Story Andre Damons | Photo Supplied

Prof Nyaga — Prof Martin Nyaga at the UFS-NGS Unit sequencing room giving a talk on the Illumina NextSeq 2000 with the P3 flow cell in hand.

The University of the Free State – Next Generation Sequencing (UFS-NGS) Unit hosted a pioneering scholarly engagement initiative for Grade 11 learners from nine secondary schools in Bloemfontein. The three-day event with the theme "Frontiers of Discovery: Illuminating the Impact of Genomics in Science outreach programme” marked the first comprehensive genomics science outreach initiative in the Faculty Health Sciences.

Coordinated by Prof Martin Nyaga, Head of the UFS-NGS Unit, the programme bridged the longstanding gap through practical NGS exposure and ignited a passion for Science, Technology, Engineering, and Mathematics (STEM) by inspiring the next generation of genomic innovators using combined interactive lectures, laboratory demonstrations, career talks, and hands-on workshops. This allowed learners to directly engage with cutting-edge scientific techniques and genomic technologies, especially the scientific and evolutionally impact of Polymerase Chain Reaction (PCR) and NGS.

The initiative engaged selected Grade 11 learners from the nine schools: Brebner, Ikaelelo and Vulamasango (day 1), Atlehang, Castle Bridge School and Kaelang (day 2) and Eunice, Navalsig, and Lekhulong (day 3).

“This outreach programme marks a significant milestone in community-based genomics education in South Africa by offering high school learners the opportunity to engage with modern genomic sciences before making career decisions. The initiative particularly aimed to nurture future scientists and diversify the country’s STEM talent pipeline.

“This historic programme bridged gaps in scientific literacy and diversity in the Free State and concluded each day with a genomics quiz competition, which tested the participant’s newly acquired knowledge/exposure and provided a fun competitive learning opportunity. Six quiz winners across the three days received special prizes, and all students were awarded certificates of participation,” says Prof Nyaga.

Hands-on exploration and NHLS virology laboratory tour

The training was held at the UFS-NGS Unit in the School of Biomedical Sciences and at the NHLS Virology laboratories, School of Pathology, Faculty of Health Sciences. Each attending secondary school was represented by five Grade 11 learners and a life science’s educator. Each day, 15 learners and three educators observed hands-on practicals, including DNA extraction, PCR, gel electrophoresis, and DNA library preparation for sequencing on platforms such as Illumina MiSeq and NextSeq 2000.

Guided by the UFS-NGS Unit’s team members; Dr Milton Mogotsi, Hlengiwe Sondlane, Mbali Ncube, Nkosazana Shange, Somila Nazo, Sesiyanda Maseko, Surprise Baloyi, Manyi Eyong and Mamello Maku, the learners were exposed to how DNA is extracted and visualised, how the PCR machine works and how DNA libraries are prepared and sequenced.

Furthermore, a guided laboratory tour of the Virology laboratories at the NHLS was provided by Khauhelo Mafa which offered the leaners the opportunity to observe, diagnostic and molecular workflows in action, resulting in a real-time glimpse into world-class medical research and diagnostics, fuelling curiosity about the role of advanced genomics science in disease control.

Inspiration through expert talks

The learners were also inspired by talks from Prof Chris Viljoen, Head of the School of Biomedical Sciences, Prof Zinhle Makatini, Associate Professor and Head of Division of Virology, School of Pathology, and Dr Claudia Ntsapi, Senior Lecturer and researcher in the Department of Basic Medical Sciences at the UFS. Prof Viljoen highlighted the role of science in transforming lives and improving life expectancy, while Prof Makatini gave candid reflections on her professional journey, particularly how she pursued Medical Virology through unwavering determination and excelled to become among the pioneer women specialists in the field in South Africa. Dr Ntsapi inspired the audience with her perseverance from her humble beginnings to earning a PhD in Neurophysiological Sciences against all odds.

The speakers also delivered compelling presentations on the applications of genomics in medicine (e.g.), personalised cancer treatments), public health (e.g.), tracking HIV and COVID-19), agriculture (e.g.), resilient crops), and environmental science (e.g.), ecosystem protection), which resonated well with the learners, educators and the UFS-NGS team. A presentation on diverse career options available at the UFS Faculty of Health Sciences was further provided by Angelique Carson-Porter, a UFS representative from the Department of Nutrition & Dietetics. Her talk on different career pathways in Health Sciences broaden the learners’ horizons, fostering future aspirations.

Dr Emmanuel Ogunbayo, Dr Mogotsi, Thabisa Mpaxa, Nkosazana Shange and Eyong Manyi shared their personal career journey to be at the UFS-NGS Unit, offering advice on academic experiences and opportunities within genomics, bioinformatics, and biotechnology, while answering scholarship queries.

“The career talk opened my eyes. I’m now aiming for a biotechnology degree!” said Neliswa Thwala, a learner from Navalsig CS/S.

Following the enthusiastic response and tangible outcomes of this programme, the UFS-NGS Unit is committed to expanding this initiative, with plans to introduce similar events to other schools and developing sustained mentorship opportunities for learners interested in pursuing genomics-related careers. The UFS-NGS Unit further invites interested partners, sponsors, and stakeholders to collaborate in future outreach and capacity-building programmes to continue bridging the genomics education gap in Africa.

Inspire the next generation

Prof. Nyaga’s closing remarks highlighted the learners’ potential to shape the ‘omics’ workforce and stated the intention of the organising committee to expand the mentorship programmes, fostering a vibrant STEM pipeline. “This initiative represents our vision to make genomics accessible and inspire the next generation of African scientists.”

The success of this programme was driven by the UFS-NGS Unit team and was supported by Distribution Platform in Omics (DIPLOMICS).

For more information about the UFS-NGS Unit or future outreach programmes, please visit our website. Further pictures from the event are also available via our website.

News Archive

Service learning teaching strategy essential for the infusion of graduate attributes

2017-01-02

Dr Pulane Pitso, Director: Institutional Performance
Monitoring within Performance Monitoring and Evaluation
Branch in the Department of the Premier, Free State
Provincial Government (FSPG).
Photo: Rulanzen Martin

“Public service delivery is not only about ‘government’s sector end products’, but is also fundamentally related to the ways in which the citizens can be best served at the point of client interface, as the primary beneficiaries.”

It is against this backdrop that Dr Pulane Pitso’s study explored the role of Higher Education Institutions (HEIs) in infusing the curriculum with graduate attributes for improved service delivery. The study is entitled: Community service learning as a transformative tool for infusing the university curriculum with graduate attributes for improved service delivery.

Citizens the central focus in public-service delivery
Although with the advent of democracy, the South African public service introduced the Batho Pele “people first” initiative which is one of the key transformation-oriented initiatives to ensure that citizens are the central focus in public service delivery. An extant literature indicates that more work by the government still needs to be done in terms of the institutionalisation and implementation thereof.

Notwithstanding that public service is primarily responsible for addressing challenges related to poor service delivery, Dr Pitso moved from a premise that a multifaceted and collaborative approach, underpinned by a concerted effort by all relevant sectors, is more likely to contribute significantly towards improving service delivery. Specific focus was given to sectors primarily mandated to lay foundations through training and development such as HEIs, since the nature and quality of public service largely depends on the nature, quality and relevance of the system of education.

CSL a transformative teaching strategy
The basis for her thesis, emanated from the contention that public service delivery is a dynamic process which cultivates into a citizen-government relationship.

“It is this relationship that makes the implementation of the Batho Pele initiative crucial in ensuring that the social fabric and moral character of government is not compromised, thus the sustainability and facilitation of the emerged relationship,” Dr Pitso says.

The study focuses on the notion of community service learning (CSL) as an increasingly recognised transformative teaching strategy. It transcends lecture halls and utilises communities as educational spaces to provide practical exposure to real-life experiences to students on both learning and serving the communities.

Instilling graduate attributes in students
Dr Pitso’s thesis, which was predominately qualitative in nature, comprised two main stages. The first stage of the study focused on determining the current state of the public service in terms of the implementation of the Batho Pele principles. Whereas with the second stage, the focus was on determining the extent to which the graduate attributes are instilled in students by means of an exit-level CSL module at the UFS.

Dr Pitso’s thesis, which was awarded to her on 30 June 2016, is the product of five years of hard work, commitment and perseverance. She said it would not have been realised if it had not been for the leadership and mentorship of her promoter, Prof Mabel Erasmus, and co-promoter, Prof Victor Teise.

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