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05 November 2025 | Story Martinette Brits | Photo Supplied
Opus Cactus
Prof Maryna Boshoff from the Department of Sustainable Food Systems and Development, Lerato Mamabolo (UFS graduate, now employed at OPUS Cactus), and Sotirios Pilafidis, Head of Research and Development at OPUS Cactus, at the XI International Congress on Cacti as Food, Fodder and Other Uses, hosted by the FAO-ICARDA CactusNet in Tenerife, Canary Islands.

The University of the Free State (UFS) has formalised a collaboration with OPUS Cactus, a pioneering biotech company focused on sustainable cactus-based farming and biorefineries in semi-arid regions. This partnership builds on OPUS Cactus’ expansion at the historic Waterkloof Research Station near Bloemfontein and combines the UFS’ academic expertise with industry innovation to promote climate-smart agriculture and economic development.

OPUS Cactus, led by Joeri van den Bovenkamp-Hofman, CEO, and Sotirios Pilafidis, Head of Research and Development (R&D), specialises in transforming marginal, non-arable land into productive, resource-efficient ecosystems by cultivating the drought-tolerant Opuntia cactus. This versatile biomass supports renewable bioenergy, animal feed, food production, fermentation feedstock, and sustainable biomaterials, while contributing to carbon capture and climate mitigation efforts.

“Our mission is to unlock the full potential of Opuntia biomass for sustainable bioenergy, food, and biomaterials, advancing regenerative agriculture and climate action,” says Van den Bovenkamp-Hofman. OPUS Cactus operates dual hubs: its headquarters and R&D lab in Groningen, the Netherlands, and the flagship 1 000-hectare Waterkloof Research Centre in the Free State. The Waterkloof facility serves as a commercial farm, research platform, and demonstration site for regenerative farming techniques.

The UFS collaboration involves multiple departments, including Sustainable Food Systems and Development, Soil, Crop and Climate Sciences, and Microbiology and Biochemistry. Profs Maryna Boshoff and Carlien Pohl-Albertyn, alongside Dr Gesine Coetzer, provide academic leadership in the partnership.

Prof Boshoff explains, “This industry-academia collaboration aims to develop innovative projects utilising cactus-based products. It builds on decades of cactus research at the UFS, enabling the translation of scientific knowledge into real-world impact through scale-up and commercialisation.”

 

Bridging academic research and commercial innovation to promote climate-smart agriculture

At the core of the partnership is the Waterkloof Research Centre, home to 42 spineless Burbank cactus pear cultivars. The facility acts as a ‘living laboratory’, integrating empirical research with commercial-scale farming. “Waterkloof now offers students and researchers access to operational infrastructure that cannot be replicated in conventional academic settings,” says Prof Boshoff.

Continuing projects at Waterkloof include biogas production through an anaerobic digester, regenerative agriculture practices such as cover cropping and reduced tillage, advanced plant biotechnology to breed superior cultivars, fermentation research for alternative proteins, and the development of novel fermented foods and sustainable biomaterials.

The collaboration also plays a critical role in conserving Opuntia genetic diversity and evaluating cultivars across South Africa’s varied agro-ecological zones. “Research done by UFS and ARC scientists on cultivar selection and cultivation is applied and scaled up through OPUS Cactus’ commercial operations,” Prof Boshoff adds.

This partnership provides valuable hands-on experience and career pathways for postgraduate students and young researchers. “We offer internships and employment opportunities, with several recent UFS graduates already joining our R&D team,” says Pilafidis. “We actively seek motivated graduates passionate about sustainable agriculture and bioengineering.”

By converting semi-arid landscapes into productive, carbon-sequestering ecosystems, the UFS-OPUS Cactus collaboration exemplifies how scientific innovation, entrepreneurship, and environmental stewardship can drive climate resilience, food security, and sustainable economic growth.

“OPUS Cactus is a win for the environment, communities, and business alike,” concludes Van den Bovenkamp-Hofman.

News Archive

UFS cardiologists and surgeons give children a beating heart
2015-04-23

Photo: René-Jean van der Berg

A team from the University of the Free State School for Medicine work daily unremittingly to save the lives of young children who have been born with heart defects by carrying out highly specialised interventions and operations on them. These operations, which are nowadays performed more and more frequently by cardiologists from the UFS School of Medicine, place the UFS on a similar footing to world-class cardiology and cardio-thoracic units.

One of the children is seven-month-old Montsheng Ketso who recently underwent a major heart operation to keep the left ventricle of her heart going artificially.

Montsheng was born with a rare, serious defect of the coronary artery, preventing the left ventricle from receiving enough blood to pump to the rest of the body.

This means that the heart muscle can suffer damage because these children essentially experience a heart attack at a very young age.

In a healthy heart, the left ventricle receives oxygenated blood from the left atrium. Then the left ventricle pumps this oxygen-rich blood to the aorta whence it flows to the rest of the body. The heart muscle normally receives blood supply from the oxygenated aorta blood, which in this case cannot happen.

Photo: René-Jean van der Berg

“She was very ill. I thought my baby was going to die,” says Mrs Bonizele Ketso, Montsheng’s mother.

She says that Montsheng became sick early in February, and she thought initially it was a tight chest or a cold. After a doctor examined and treated her baby, Montsheng still remained constantly ill, so the doctor referred her to Prof Stephen Brown, paediatric cardiologist at the UFS and attached to Universitas Hospital.

Here, Prof Brown immediately got his skilled team together as quickly as possible to diagnose the condition in order to operate on Montsheng.

During the operation, the blood flow was restored, but since Montsheng’s heart muscle was seriously damaged, the heart was unable to contract at the end of the operation. Then she was coupled to a heart-lung machine to allow the heart to rest and give the heart muscle chance to recover. The entire team of technologists and the dedicated anaesthetist, Dr Edwin Turton, kept a vigil day and night for several days.

Prof Francis Smit, chief specialist at the UFS Department of Cardiothoracic Surgery, explains that without this operation Montsheng would not have been able to celebrate her first birthday.

“After the surgery, these children can reach adulthood without further operations. Within two to three months after the operation, she will have a normal active life, although for about six months she will still use medication. Thereafter, she will be tiptop and shortly learn to crawl and walk.”

Mrs Ketso is looking forward enormously to seeing her daughter stand up and take her first steps. A dream which she thought would never come true.    

“Write there that I really love these doctors.”

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