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21 October 2025 | Story André Damons | Photo André Damons
Nuclear Medicine
Smiling proudly are Dr Gerrit Engelbrecht, Head of the UFS Department of Nuclear Medicine, Dr Tebatso Tebeila, senior resident in the same department, and Prof Osayande Evbuomwan, Senior Lecturer and medical specialist in nuclear medicine in the Department of Nuclear Medicine, with the certificate indicating they are now a Clinical Theranostics Centre of Excellence.

The Department of Nuclear Medicine at the Universitas Academic Hospital (UAH) and the University of the Free State (UFS) have been certified as Clinical Theranostics Centers of Excellence from the International Centers for Precision Oncology Foundation (ICPO). The hospital now joins only two other centres in South Africa to achieve this prestigious recognition.

The certification followed a rigorous evaluation process by the ICPO Foundation, which assessed the department’s clinical standards, infrastructure, expertise, and commitment to advancing theranostics. The application and verification process was done by Dr Tebatso Tebeila, a senior resident at the department who has just passed her final exams. She was supported by Dr Gerrit Engelbrecht, Head of the UFS Department of Nuclear Medicine, in the process which included interviews with the ICPO accreditation and projects director Dr Marwa Hakkam. Dr Tebeila had also completed the ICPO short course in Radiomolecular Precision Oncology through the ICPO Academy of Theranostics.

The UAH Nuclear Medicine Department began theranostics activities about five years ago, particularly in neuroendocrine and prostate malignancies. Prof Osayande Evbuomwan, Senior Lecturer and medical specialist in nuclear medicine in the UFS Department of Nuclear Medicine, received training for this during his residency period and had completed a rigorous international training workshop organised by the International Atomic Energy Agency on theranostics, particularly in prostate cancer, neuroendocrine neoplasms and well differentiated thyroid cancer. Prof Evbuomwan passed all these training and skills down to the department. The certification was further strengthened by the installation of department’s new state-of-the-art digital PET/CT camera, placing it on par with similar academic departments in the country. The recognition was officially conferred during the ICPO Reception at the European Association of Nuclear Medicine Congress in Barcelona earlier this month.  

 

A milestone achievement

“Being granted this certification signifies international recognition of our hospital’s commitment to the highest clinical, academic, and ethical standards in theranostics. It confirms that our institution meets the global benchmarks for delivering precision oncology care that integrates diagnostics and therapy for personalised cancer management.

“For our department and the University of the Free State, this is a milestone achievement that highlights our leadership in nuclear medicine and molecular imaging. It strengthens our research and training capacity and also attracts residents who want to be trained in nuclear medicine. It also enhances collaboration with international partners and aligns with our mission to advance precision medicine in South Africa and beyond,” says Prof Evbuomwan.

Theranostics, he explains, is an aspect of nuclear medicine that involves the use of a tracer bound to a radioisotope that can specifically locate and image cancer cells with high precision, characterise them and determine how much radiation will get to them. Using the same tracer, but a different radioisotope for therapy, these cancer cells are targeted with high precision and destroyed. It could be so precise that it targets only the cancer, sparing most of the normal tissue and thus resulting in less serious side effects. It is an aspect of nuclear medicine that is bound to revolutionise cancer care.

Dr Gerrit Engelbrecht says as a department, they are honoured and deeply proud of this achievement as it reflects months of dedication, innovation, and teamwork. “It validates our commitment to excellence in improving patient care and academic advancement, and we are motivated to build on this success. We are also grateful to Dr Tebeila for her initiative, hard work, dedication and networking skills.

“We would like to thank the ICPO Foundation for this recognition and for its continued efforts to support theranostics in developing regions. We also acknowledge the hard work of our staff, and partners who made this possible. This milestone inspires us to continue driving innovation and equitable access to precision oncology in Bloemfontein, the Free State province and South Africa at large.”

 

Forefront of precision oncology 

According to Prof Evbuomwan, patients will also benefit from this certification as it translates to improved access to world-class, and evidence-based theranostic management. It means earlier diagnosis, more accurate therapy selection, and ultimately, better treatment outcomes and quality of life for those with some of these cancers. They strongly believe the patients in the Free State also deserve access to this management, as the world is now moving slowly into the era of personalised and precision medicine. The Universitas Academic Hospital is now among three centres in South Africa (Numeri in SBAH Pretoria and Umhlanga Molecular Imaging and Therapy Centre in Durban) to achieve this prestigious recognition, joining an international network of 46 centres, mostly located in low- and middle-income countries. This positions the UFS at the forefront of precision oncology on the African continent.

Prof Evbuomwan says they hope to use this new status to expand patient access to theranostic treatments, foster multidisciplinary collaborations within the Universitas academic circuit, and participate in global research initiatives through the ICPO Academy for Theranostics. Certifications like this, he continues, would also help to attract more staff and junior resident doctors to the facility. It will also help them train the next generation of nuclear medicine specialists and strengthen South Africa’s role in precision oncology. The ICPO will also offer direct assistance to the facility to achieve these objectives.

On her trip to the EANM Congress in Barcelona to receive the certificate and to attend the international congress, Dr Tebeila said it is always such an honour to attend international conferences and this year’s EANM was particularly invigorating with the latest scientific presentations in various theranostic applications by peers and well-known experts in the global nuclear medicine sphere. 

“The highlight was, of course, attending the annual Oncidium Foundation Ambassadors meeting and being part of the ICPO certification ceremony along with my counterparts from 23 other centres spanning Asia, Arab regions and Africa. 

“My wish is to see the UAH nuclear medicine department grow in leaps and bounds, epically in patient reach, clinical research with academic expansion and overall excellence in service delivery. This ICPO theranostics centre of excellence certification is only the beginning of what is to come.”

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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