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21 October 2025 | Story André Damons | Photo André Damons
Nuclear Medicine
Smiling proudly are Dr Gerrit Engelbrecht, Head of the UFS Department of Nuclear Medicine, Dr Tebatso Tebeila, senior resident in the same department, and Prof Osayande Evbuomwan, Senior Lecturer and medical specialist in nuclear medicine in the Department of Nuclear Medicine, with the certificate indicating they are now a Clinical Theranostics Centre of Excellence.

The Department of Nuclear Medicine at the Universitas Academic Hospital (UAH) and the University of the Free State (UFS) have been certified as Clinical Theranostics Centers of Excellence from the International Centers for Precision Oncology Foundation (ICPO). The hospital now joins only two other centres in South Africa to achieve this prestigious recognition.

The certification followed a rigorous evaluation process by the ICPO Foundation, which assessed the department’s clinical standards, infrastructure, expertise, and commitment to advancing theranostics. The application and verification process was done by Dr Tebatso Tebeila, a senior resident at the department who has just passed her final exams. She was supported by Dr Gerrit Engelbrecht, Head of the UFS Department of Nuclear Medicine, in the process which included interviews with the ICPO accreditation and projects director Dr Marwa Hakkam. Dr Tebeila had also completed the ICPO short course in Radiomolecular Precision Oncology through the ICPO Academy of Theranostics.

The UAH Nuclear Medicine Department began theranostics activities about five years ago, particularly in neuroendocrine and prostate malignancies. Prof Osayande Evbuomwan, Senior Lecturer and medical specialist in nuclear medicine in the UFS Department of Nuclear Medicine, received training for this during his residency period and had completed a rigorous international training workshop organised by the International Atomic Energy Agency on theranostics, particularly in prostate cancer, neuroendocrine neoplasms and well differentiated thyroid cancer. Prof Evbuomwan passed all these training and skills down to the department. The certification was further strengthened by the installation of department’s new state-of-the-art digital PET/CT camera, placing it on par with similar academic departments in the country. The recognition was officially conferred during the ICPO Reception at the European Association of Nuclear Medicine Congress in Barcelona earlier this month.  

 

A milestone achievement

“Being granted this certification signifies international recognition of our hospital’s commitment to the highest clinical, academic, and ethical standards in theranostics. It confirms that our institution meets the global benchmarks for delivering precision oncology care that integrates diagnostics and therapy for personalised cancer management.

“For our department and the University of the Free State, this is a milestone achievement that highlights our leadership in nuclear medicine and molecular imaging. It strengthens our research and training capacity and also attracts residents who want to be trained in nuclear medicine. It also enhances collaboration with international partners and aligns with our mission to advance precision medicine in South Africa and beyond,” says Prof Evbuomwan.

Theranostics, he explains, is an aspect of nuclear medicine that involves the use of a tracer bound to a radioisotope that can specifically locate and image cancer cells with high precision, characterise them and determine how much radiation will get to them. Using the same tracer, but a different radioisotope for therapy, these cancer cells are targeted with high precision and destroyed. It could be so precise that it targets only the cancer, sparing most of the normal tissue and thus resulting in less serious side effects. It is an aspect of nuclear medicine that is bound to revolutionise cancer care.

Dr Gerrit Engelbrecht says as a department, they are honoured and deeply proud of this achievement as it reflects months of dedication, innovation, and teamwork. “It validates our commitment to excellence in improving patient care and academic advancement, and we are motivated to build on this success. We are also grateful to Dr Tebeila for her initiative, hard work, dedication and networking skills.

“We would like to thank the ICPO Foundation for this recognition and for its continued efforts to support theranostics in developing regions. We also acknowledge the hard work of our staff, and partners who made this possible. This milestone inspires us to continue driving innovation and equitable access to precision oncology in Bloemfontein, the Free State province and South Africa at large.”

 

Forefront of precision oncology 

According to Prof Evbuomwan, patients will also benefit from this certification as it translates to improved access to world-class, and evidence-based theranostic management. It means earlier diagnosis, more accurate therapy selection, and ultimately, better treatment outcomes and quality of life for those with some of these cancers. They strongly believe the patients in the Free State also deserve access to this management, as the world is now moving slowly into the era of personalised and precision medicine. The Universitas Academic Hospital is now among three centres in South Africa (Numeri in SBAH Pretoria and Umhlanga Molecular Imaging and Therapy Centre in Durban) to achieve this prestigious recognition, joining an international network of 46 centres, mostly located in low- and middle-income countries. This positions the UFS at the forefront of precision oncology on the African continent.

Prof Evbuomwan says they hope to use this new status to expand patient access to theranostic treatments, foster multidisciplinary collaborations within the Universitas academic circuit, and participate in global research initiatives through the ICPO Academy for Theranostics. Certifications like this, he continues, would also help to attract more staff and junior resident doctors to the facility. It will also help them train the next generation of nuclear medicine specialists and strengthen South Africa’s role in precision oncology. The ICPO will also offer direct assistance to the facility to achieve these objectives.

On her trip to the EANM Congress in Barcelona to receive the certificate and to attend the international congress, Dr Tebeila said it is always such an honour to attend international conferences and this year’s EANM was particularly invigorating with the latest scientific presentations in various theranostic applications by peers and well-known experts in the global nuclear medicine sphere. 

“The highlight was, of course, attending the annual Oncidium Foundation Ambassadors meeting and being part of the ICPO certification ceremony along with my counterparts from 23 other centres spanning Asia, Arab regions and Africa. 

“My wish is to see the UAH nuclear medicine department grow in leaps and bounds, epically in patient reach, clinical research with academic expansion and overall excellence in service delivery. This ICPO theranostics centre of excellence certification is only the beginning of what is to come.”

News Archive

Stem cell research and human cloning: legal and ethical focal points
2004-07-29

   

(Summary of the inaugural lecture of Prof Hennie Oosthuizen, from the Department of Criminal and Medical Law at the Faculty of Law of the University of the Free State.)

 

In the light of stem cell research, research on embryo’s and human cloning it will be fatal for legal advisors and researchers in South Africa to ignore the benefits that new bio-medical development, through research, contain for this country.

Legal advisors across the world have various views on stem cell research and human cloning. In the USA there is no legislation that regulates stem cell research but a number of States adopted legislation that approves stem cell research. The British Parlement gave permission for research on embryonic stem cells, but determined that it must be monitored closely and the European Union is of the opinion that it will open a door for race purification and commercial exploitation of human beings.

In South Africa the Bill on National Health makes provision for therapeutical and non therapeutical research. It also makes provision for therapeutical embryonical stem cell research on fetuses, which is not older than 14 days, as well as for therapeutical cloning under certain circumstances subject to the approval of the Minister. The Bill prohibits reproductive cloning.

Research on human embrio’s is a very controversial issue, here and in the rest of the world.

Researchers believe that the use of stem cell therapy could help to side-step the rejection of newly transplanted organs and tissue and if a bank for stem cell could be built, the shortage of organs for transplants would become something of the past. Stem cells could also be used for healing of Alzheimer’s, Parkinson’s and spinal injuries.

Sources from which stem cells are obtained could also lead to further ethical issues. Stem cells are harvested from mature human cells and embryonic stem cells. Another source to be utilised is to take egg cells from the ovaries of aborted fetuses. This will be morally unacceptable for those against abortions. Linking a financial incentive to that could become more of a controversial issue because the woman’s decision to abort could be influenced. The ideal would be to rather use human fetus tissue from spontaneous abortions or extra-uterine pregnancies than induced abortions.

The potential to obtain stem cells from the blood of the umbilical cord, bone-marrow and fetus tissue and for these cells to arrange themselves is known for quite some time. Blood from the umbilical cord contains many stem cells, which is the origin of the body’s immune and blood system. It is beneficial to bank the blood of a newborn baby’s umbilical cord. Through stem cell transplants the baby or another family member’s life could be saved from future illnesses such as anemia, leukemia and metabolic storing disabilities as well as certain generic immuno disabilities.

The possibility to withdraw stem cells from human embrio’s and to grow them is more useable because it has more treatment possibilities.

With the birth of Dolly the sheep, communities strongly expressed their concern about the possibility that a new cloning technique such as the replacement of the core of a cell will be used in human reproduction. Embryonic splitting and core replacement are two well known techniques that are associated with the cloning process.

I differentiate between reproductive cloning – to create a cloned human embryo with the aim to bring about a pregnancy of a child that is identical to another individual – and therapeutically cloning – to create a cloned human embryo for research purposes and for healing human illnesses.

Worldwide people are debating whether to proceed with therapeutical cloning. There are people for and against it. The biggest ethical objection against therapeutical cloning is the termination of the development of a potential human being.

Children born from cloning will differ from each other. Factors such as the uterus environment and the environment in which the child is growing up will play a role. Cloning create unique children that will grow up to be unique individuals, just like me and you that will develop into a person, just like you and me. If we understand this scientific fact, most arguments against human cloning will disappear.

Infertility can be treated through in vitro conception. This process does not work for everyone. For some cloning is a revolutionary treatment method because it is the only method that does not require patients to produce sperm and egg cells. The same arguments that were used against in vitro conception in the past are now being used against cloning. It is years later and in vitro cloning is generally applied and accepted by society. I am of the opinion that the same will happen with regard to human cloning.

There is an argument that cloning must be prohibited because it is unsafe. Distorted ideas in this regard were proven wrong. Are these distorted ideas justified to question the safety of cloning and the cloning process you may ask. The answer, according to me, is a definite no. Human cloning does have many advantages. That includes assistance with infertility, prevention of Down Syndrome and recovery from leukemia.

 

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